Flashcards
ANS LECTURE 1
Cards in this deck (24)
- 1ANS LECTURE 1 : What are the divisions of the autonomic nervous system?Parasympathetic and Sympathetic Nervous System
- 2ANS LECTURE 1 : What type of neurotransmitter is found in the Sympathetic Nervous System?Norepinephrine/Noradrenaline
- 3ANS LECTURE 1 : What neurotransmitter is found in the parasympathetic nervous system?Acetylcholine
- 4ANS LECTURE 1 : What receptor is found in the parasympathetic nervous system?Cholinergic
- 5ANS LECTURE 1 : What receptor is found in the sympathetic nervous system?Adrenergic
- 6ANS LECTURE 1 : What are some examples of adrenergic receptors?Alpha-1, 2
Beta-1,2,3
Dopamine - 7ANS LECTURE 1 : What are some examples of cholinergic receptors?Muscarinic
Nicotinic - 8ANS LECTURE 1 : What receptor category does nicotinic receptors lay?Ligand Gated Ion channels
- 9ANS LECTURE 1 : What receptor category does muscarinic receptors lay?G-protein coupled receptors
- 10ANS LECTURE 1 : What is the effect of neurotransmitter's on ANS?Their job is to carry chemical signals (“messages”) from one neuron (nerve cell) to the next target cell.
- 11ANS LECTURE 1 : What are the steps involved in cholinergic transmission
- 12ANS LECTURE 1 : What are the steps involved in adrenergic transmission
- 13ANS LECTURE 1 : Where are the M1, M2, M3 receptors found?M1- CNS, Gastric gland, Salivary gland
M2 - Heart, GIT, CNS
M3 - Gastric gland, Salivary gland, Eye, GIT, Blood vessels - 14ANS LECTURE 1 : Where are specific beta adrenergic receptors found ?β1 - Heart , Salivary gland
β2 - Blood vessels
Bronchi , GIT, Uterus, Bladder - 15ANS LECTURE 1 : Where are specific alpha adrenergic receptors found ?α1- Uterus ,Bladder , Iris
α2 -Blood vessels, GIT, Pancreas - 16ANS LECTURE 1 : What three mechanisms are involved in the termination of neurotransmitter's?Diffusion out of the cleft
Enzymatic conversion
Uptake (uptake 1 and uptake 2) - 17ANS LECTURE 1 : Why must neurotransmitters be diffused out of the synapse?To prevent exaggerated or extended stimulation of effector organs
- 18ANS LECTURE 1 : How is Acetylcholine terminated ?Hydrolysis by the extremely rapid-acting enzyme acetylcholinesterase. Hydrolyzed into acetate(inactive), and choline
- 19ANS LECTURE 1 : How is Norepinephrine terminated ?NE is transported back into the nerve by Uptake 1. This process can be inhibited by cocaine.
- 20ANS LECTURE 1 : Define an Antagonist?A molecule, such as a drug physiologic agent (e.g., hormone), that diminishes or prevents the action of another molecule.
- 21ANS LECTURE 1 : Define an Agonist?A drug that has properties similar to a natural ligand in activating the same receptor.
- 22ANS LECTURE 1 : What are the mode of actions of an agonist?- Direct acting and indirect acting
- 23ANS LECTURE 1 : What is a direct acting agonist?Molecule that physically binds to the target for its effect.
eg. carbachol activates cholinergic receptors. - 24ANS LECTURE 1 : What is a indirect acting agonist?Molecule that exerts effect on the target by interacting with another non-target site.
eg. neostigmine blocks AchE, causing Ach accumulation.
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- Flashcards on ANS LECTURE 1, created by Kali Hillary on 19/09/2022.
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- Kali Hillary
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