Flashcards
Immune Cells
Cards in this deck (22)
- 1Macrophage (function)Phagocytose pathogens and dead cells
- 2Macrophage (differential factors)IL-3
M-CSF
GM-CSF
TNF - 3Dendritic Cells (function)Antigen Presenting Cell (APC)
Activate T Helper Cells - 4Dendritic Cells (differential factors)IL-4, TGF-β
M-CSF (less stimulatory to T cell)
GM-CSF (more stimulatory to T cell) - 5what do macrophages and dendritic cells have in common?they both come from monocytes
- 6Do macrophages circulate in the blood?no
- 7Phagocytic granulocytesNeutrophils and Eosinophils
- 8are monocytes granulocytes?no
- 9Neutrophils stain with what?acid and basic dye (they are NEUTRAL)
- 10Main features of NEUTROPHILSPMN (multi-lobed nucleus)
Primary and secondary granules - 11Primary granules includelysozyme
peroxidase
hydrolytic enzymes - 12Secondary granules includelysozymes
lactoferrin
collagenase - 13Neutrophil (differentiation factors)IL-3
IL-6
G-CSF
GM-CSF - 14Eosinophil (function)Phagocytose PARASITES by digesting membranes with enzymes
- 15Main feature of EOSINOPHILSBi-lobed nucleus
Stain with acid (eosin >> eosinophil) - 16Eosinophil (differential factors)IL-3
IL-5
GM-CSF - 17Basophil (function)Mediates ALLERGIC response
Release histamine - 18Main features of basophillobed nucleus
stains with BASIC (methyin blue) dye >> basophil - 19Basophil (differential factors)IL-3
IL-6
G-CSF
GM-CSF - 20Mast Cells (function)allergic and inflammatory MEDIATOR (ie increase vascular permeability, vasodilation, attract NEUTOROPHILS, release histamine)
- 21Which receptor activates Mast Cells?IgE (so an IgE antibody attaches to an IgE receptor on Mast Cell)
- 22Describe mast cell activationFce ligand binds to IgE antibody on mast cell surface.
Antigen binding to IgE causes CROSS-LINKING of IgE and results in granule contents release via chain reaction
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- Flashcards on Immune Cells, created by Alice Brealy on 09/02/2016.
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- Alice Brealy
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