Cell Signalling lecture

Question	Answer
What are the key components of a signalling pathway?	Ligand, Receptor, Transducer & Effector
Name the 5 key developmental signalling pathways	Hedgehog Pathway Notch Pathway Wnt Pathway TGFB Pathway FGF Pathway
Name the ligand, receptor, transducer & effector of the hedgehog pathway	Ligand: Sonic hedgehog (Shh) receptor: patched transducer: Smoothered Effector: Gli (2 & 3)
Name the ligand, receptor, transducer & effector of the Notch pathway	ligand: Delta Receptor: Notch Transducer: NICD Effector: RBPjK
Name the ligand, receptor, transducer & effector of the Wnt Pathway	ligand: Wnt Receptor: frizzled/LRP transducer: Dishevelled effector: B-canetin
Name the ligand, receptor, transducer & effector of the FGF pathway	ligand: FGF receptor: FGFR transducer: ERK/AKT effector: ETS
How does cell signalling come about?	Endocrine: through bloodstream Paracrine: neighboring cells Autocrine: cell releases signal & captures it itself

Resource summary

	Created by Sophia Puliasis over 7 years ago