Flashcards
Pharmacology of T2DM
Cards in this deck (5)
- 1Metformin1st line treatment
+ liver --> - GNG
SE: GI disturbance, lactic acidosis - 2Sulphonureas1st line treatment
+SU Rs, K+ATP, +B cells -> Increased insulin release
SE: Hypoglycaemia and weight gain - 3InsulinLate stage treatment
Increases glucose uptake (liver, muscle, fat)
SE: hypoglycaemia and weight gain - 4Thiazolidine diones (Rosiglitazone/Avonida)+PPAR gamma increasing gene transcription of Insulin Rs in fat, liver and muscle, increases insulin sensitivity, reduces FFAs in circulation
SE: CVD? - 5Acarbosealpha glucosidase in intestine
SE: GI disturbance
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- under grad Endocrine Pharmacology Flashcards on Pharmacology of T2DM, created by Bhavi Mistry on 31/05/2013.
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- Bhavi Mistry
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