Flashcards
Metoprolol pharmacokinetics
Cards in this deck (6)
- 1The steps in pharmacokineticsDADME
Dissolution
Absorption
Distribution
Metabolism
Excretion - 2DissolutionEasily dissolved in the stomach and GIT
- 3AbsorptionQuickly and readily absorbed by the GIT into circulation
- 4DistributionQuickly distributed across the body (3 - 6 hour half-life) Can cross the blood-brain barrier, and cross the placenta as well as enter breast milk.
- 5MetabolismHas a 50% oral bioavailability due to the first pass effect - readily metabolised by the liver - into three different metabolites
- 6ExcretionExtensively (95%) excreted by the kidneys as metabolites and a small amount of unmetabolised drug
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- User has deleted their subject information Flashcards on Metoprolol pharmacokinetics, created by Deleted user on 10/06/2018.
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- Created by Em J · Jun 10, 2018
- Copied by Em J · Jun 10, 2018
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