Flashcards
HPA - Lactulose
Cards in this deck (13)
- 1What is it?An osmotic laxative
- 2Trade namesActilax, Duphalac, Genlac, Lac-Dol, Lactour
- 3Pharmacological classGlycoside
- 4IndicationsChronic constipation
hyperammonemia ( caused by hepatic encephalopathy) - 5ActionProduces an osmotic effect in colon; resulting distension promotes peristalsis. Also decreases blood ammonia level by drawing ammonia from circulation into the colon and through the GIT
- 6Therapeutic effectsSoftens stools and removes ammonia from circulation
- 7Absorption and distributionABSORPTION: poorly absorbed by GIT
DISTRIBUTION: primarily in the colon - 8Metabolism & excretionmetabolised in the colon by enteric bacteria. Fecal excretion
- 9Half life1.7 - 2 hours
- 10PrecautionContraindicated in individuals on low-galactose or lactose-free diets
Use cautiously in individuals with DM
Be prepared to replace fluid loss - 11Side effectsAbdominal cramping, flatulence, nausea and vomiting, diarrhoea, dehydration and electrolyte disturbances
- 12InteractionsAntacids, antibiotics: decreased effectiveness of lactulose. Avoid use together.
- 13EducationInstruct patient not to take other laxatives
Encourage person to exercise, as tolerated
Advise patient to notify prescriber if diarrhoea occurs
Educate patient regarding dietary fiber
Tell patient to keep up fluids
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- User has deleted their subject information Flashcards on HPA - Lactulose, created by Deleted user on 10/06/2018.
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- Created by Em J · Jun 10, 2018
- Copied by Em J · Jun 10, 2018
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