Flashcards
ANS 2
Cards in this deck (16)
- 1Sympathetic system & NeurotransmitterPre-ganglion= Acetycholine
Post-ganglion= Adrenaline/Noradrenaline - 2Parasympathetic system & NeurotransmitterPre and post-ganglion= Acetycholine
- 3ANS- Neurotransmitters and Receptors (SNS)AP travels down sympathetic preganglionic fibre--> triggers release of ACh at the junction--> binds to nicotinic receptor in postganglion--> signal continues to travel down postganglionic fibre--> triggers release of Noradrenaline/Adrenaline--> binds to alpha/beta receptors
- 4ANS- Neurotransmitters and Receptors (PNS)AP travels down sympathetic preganglionic fibre--> triggers release of ACh at the junction--> binds to nicotinic receptor in postganglionic neuron--> signal continues to travel down postganglionic fibre--> triggers release of ACh--> binds to muscarinic receptors
- 5Adrenergic Receptors Cholinergic ReceptorsAdrenergic receptors= alpha 1 & 2, beta 1 & 2
Cholinergic Receptors= Nicotinic and Muscarinic Receptors - 6Nicotinic receptorsSite of receptor= all autonomic ganglia
(Motor end plate of skeletal muscle fibres and some CNS cell bodies and dendrites)
Response to ACh= Sympathetic and parasympathetic preganglionic fibres - 7Muscarinic receptorsSite of receptor= Effector cells (cardiac muscle, smooth muscle, glands)
Response to ACh= Parasympathetic postganglionic fibres - 8Alpha 1- higher affinity for noradernaline than adrenaline
- Ca 2+ second messenger system
- Excitatory response, contraction of smooth muscles
- arterioles, most sympathetic target tissues - 9Alpha 2- higher affinity for noradernaline than adrenaline
- Blocks cyclic AMP production
- Inhibitory response, relaxation of smooth muscle
- digestive tract (digestion slows down) - 10Beta 1- same affinity for noradrenaline and adrenaline
- Cyclic AMP second messenger system
- excitatory response (heart beats faster)
- Heart (kidney, liver) - 11Beta 2- more affinity for adrenaline
- Cyclic AMP second messenger system
- inhibitory response (relaxation of smooth muscle)
- Bronchioles, arterioles (causes bronchioles to dilate which helps us to breath easier) - 12Beta 1 antagonist- selectively blocks beta 1 adrenergic receptors reducing the sympathetic effects on the heart
- reduces heart rate in treatment of hypertension - 13Beta 2 agonist- dilates bronchioles in the treatment of asthma without undesirably stimulating the heart
- selectively activates β2 adrenergic receptors at low doses thereby relaxing the bronchial smooth muscles (the heart has mostly β1 adrenergic receptors) - 14Muscarinic antagonist- suppresses salivary and bronchial secretions before surgery
- selectively blocks ACh at the muscarinic receptors, thereby blocking the parasympathetic effects - 15Nicotinic antagonist- reduces the effects of both SNS and PNS
- 16Adrenaline- Increase HR and leads to general vasoconstriction in the treatment of acute heart failure
- Adrenaline activates α & β receptors thereby increasing HR, and promoting smooth muscle contraction of peripheral arterioles, which results in increased arterial blood pressure
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- PHYL2065 Flashcards on ANS 2, created by Ahrani Vaheesan on 22/08/2019.
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- Ahrani Vaheesan
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