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Hyposecretion of prolactin

Little milk synthesis and secretion

Prolactinoma tumour affecting lactotroph cells

Hypersection of prolactin

Males

Females

Gynecomastia

Low testosterone

Galactorrhea: Breast development in non lactating

Amenorrhea: Failure of menstrual cycle

Vasopressin actions

Retains water

Increase blood pressure

Vasopressin regulation

Blood volume

Solute concentration

Increase in blood volume by water retention

Stretch receptor in veins activated

Vasopressin neurons turned off

Increase in water excretion

Lower blood volume

Osmoreceptors regulate solute

Osmoregulators relay back to vasopressin neurons