Chemistry In Context II Mental Map

Chemistry In Context II Mental Map

1. Any chemical you take that affects the way your body works.

2. Pharmacology

   • Legal Prescription Drug
     • Passed trough a lot of scientific investigation.
     • Types
       • Opioids
       • Depressants
       • Stimulants
     • Medications
       • Original
         • Developed by pharmaceutical companies
       • Generic
         • Bioequivalence
           • Same effect as the original
       • Similar
         • Only have pharmacopoeia information
           • Not the same effect as the original
   • Illegal Drug
     • Do not go trough any kind of research
     • Medications
       • % falsified/adulterated per year
         • Mexico: 20-50%
         • USA: Less than 1%
         • EU: Less than 1%
         • China: 11-20%
       • Economical Repercussions
         • Decreased revenues of pharmaceutical companies
       • Health Effects
         • Death
         • Hepatic Insuffiency
         • Intoxication
       • Most affected
         • Countries
           • Weaker regulatory systems and enforcement of the law on medical products.
             • Africa
             • Asia
             • Latin America
         • People
           • Internet
             • Illegal Sites
               • Doesn’t show their physical location.

3. Functional Groups

   • To know how does the human being´s body is going to react with the substance developed

4. Alkaloids

   • Basic Unit:Amino Acids
   • Founded in plants
     • 3,000 different types
   • Examples
     • Morphine
     • Nicotine
     • Strychnine

5. Drug Development

   • 1- Discovery
   • 2- Product Characterization
   • 3- Formulation, Delivery, Packaging Development
   • 4- Pharmacokinetics And Drug Disposition
   • 5- Preclinical Toxicology Testing And IND Application
   • 6- Bioanalytical Testing
   • 7- Clinical Trials

6. Economy

   • Develop a single drug
     • $802 million dollars