2044716
Description
Mind Map by Laura Smitherman, updated more than 1 year ago
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Created by Laura Smitherman
about 9 years ago
|
|
Antiphospholipid
syndrome
- Cause
- autoimmune
- ?antiphospholipid antibodies
- lupus
anticoagulant
- anti-cardiolipin
- anti-β2-glycoprotein-I
- lupus
anticoagulant
- complement
and platelet
activation
- ?antiphospholipid antibodies
- genetic
- unknown
- autoimmune
- presentation
- hypercoagulable state
- venous
- DVT
- PE
- DVT
- arterial
- stroke
- stroke
- venous
- pregnancy complications
- stillbirth
- miscarriage
- preterm
delivery
- severe
pre-eclampsia
- stillbirth
- Livedo reticularis
- haemolytic
anaemia
- thrombocytopenia
- hypercoagulable state
- Types
- Primary
- HLA-DR7
- HLA-DR7
- Secondary
- risk factors
- associated with
other
autoimmune
diseases e.g. SLE, RA
- HLA-B8,
HLA-DR2,
HLA-DR3
- ethnicity
- most
common in
young
fertile
women
- associated with
other
autoimmune
diseases e.g. SLE, RA
- risk factors
- Primary
- Management
- Lifestyle to
reduce
cardiovascular
risks
- Thrombosis risk
- Acute
- Heparin
- Heparin
- Long term
- Warfarin (INR 2-3) or antiplatelet
- Warfarin (INR 2-3) or antiplatelet
- Acute
- In pregnancy
- LMWH + aspirin
- LMWH + aspirin
- Lifestyle to
reduce
cardiovascular
risks
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