Staphylococcus Aureus

Staphylococcus Aureus

1. morphology

   • bunch of grapes
   • aureus colonies-golden colour
   • blood agar-B hemolytic

2. Characteristic

   • large, round, opaque
   • facultative anaerobe
   • many virulence fc
   • withstand H.salt, extreme pH, H temp
   • catalase +
   • coagulase +

3. Virulence fc

   • enzyme
     • coagulase
     • hyaluronidase
     • stayphylokinase
     • DNase
     • lipases
     • penicillinase
   • toxins
     • hemolysin
     • leukocidin
     • enterotoxin
     • exfoliative toxin
     • TSS

4. Epidemiology

   • readily isolated fomite
   • carriage-anterior nares, skin, nasopharynx, intestine
   • increase in MRSA community
   • predisposition-immunocompromised, poor hygiene, tissue injury

5. Diseases

   • localised
     • foliculitis
     • furuncle
     • carbuncle
     • impetigo
   • systemic
     • osteomyelitis
     • bacteremia
   • toxigenic
     • food intoxication
     • SSSS
     • TSS

6. Treatment

   • vancomysin
   • abscess-surgery
   • clindamysin