Quiz
PHSI3011 05-2 Maintenance of Bone Health
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Questions in this quiz (29)
1If Resorption < Formation:
- A↑ Bone Mass
- B↓ Bone Mass
2Which of the following are bone mass determinants:
- AGenetics
- BAge
- CMechanical loading
- DProtein intake
- ECalcium intake
- FVitamin D
- GSex steroids
- HVitamin C
3Sclerostin is released by which of the following?
- AOsteocytes
- BOsteoblasts
- COsteoclasts
- DLining Cells
4Sclerostin __________ Wnt signalling in Osteoblasts/Osteocytes
- AInhibits
- BStimulates
5With deformity of bone (on loading), sclerostin secretion:
- AIncreases
- BDecreases
6SOST = ??
- ASclerOSTin
- BStimulated by OSTeocyte
7Obligatory urine Calcium loss is [blank_start]__________[blank_end] mg/d (although [blank_start]__________[blank_end] after menopause).
- A150-200
- B1000
- C25
- D300
- EMore
- FLess
8Recommended daily allowance for calcium changes according to age, but broadly mostly around:
- A1000
- B70
- C150-200
- D700
- E2000
- F1500-2000
- G25
- H300
9Vitamin D [blank_start]__________[blank_end] gut Calcium absorption:
- ADecreases
- BIncreases
10A non-Calcium-rich diet will usually have approximately [blank_start]__________[blank_end] mg/d Calcium. This is [blank_start]__________[blank_end]% of recommended intake.
- A300
- B1000
- C150-200
- D30
- E15-20
- F25
- G100
- H70
11True or false: Exposure to the sun is [normally] our main source of Vitamin D.
- ATrue
- BFalse
12True or false: Diet is [normally] our main source of Vitamin D.
- ATrue
- BFalse
13What’s the recommended daily intake of Vitamin D?
- A1000IU (25μg)
- B25IU (1000μg)
14Which of the following accelerates Vitamin D degradation?
- ASome medications
- BLOW Calcium intake
- CHIGH Calcium intake
- DHIGH PTH
- ELOW PTH
15Which of the following groups are commonly associated with increased risk of Vitamin D deficiency?
- AGeriatric admissions to hospital
- BDark-skinned people, especially with modest dress
- CObese people
- DFair skinned people with severe tan
- EFair skinned people who avoid sun because of skin cancer risk
- FOffice workers
- GNight shift workers
- HFarmers
16In a study of 100 office workers in Sydney, sunscreen users had [blank_start]__________[blank_end] Vitamin D levels compared to non-users.
- AHigher
- BLower
17How does Vitamin D help bone health?
- AIncreases gut Calcium absorption
- BFacilitates bone mineralisation
- CImportant for muscle function
- DPermits release of bone stores of Calcium
- EIt doesn’t
18Vitamin D deficiency leads to increased bone turnover. Severe Vitamin D deficiency leads [primarily] to?
- AOsteomalacia
- BOsteoporosis
- CBoth of the above
- DNeither of the above
19Adequate levels of [blank_start]__________[blank_end] are needed to maximise Calcium absorption and [blank_start]__________[blank_end] ParaThyroid Hormone (PTH).
- A25OHD
- B25HD
- C25OD
- D2OH5D
- E20O5HD
- FSuppress
- GIncrease
2025OHD = ??
- A25(OH) vitamin D
- B1,25(OH) vitamin D
- C1,25(OH)2 vitamin D
- D25(OH)2 vitamin D
21Severe CALCIUM deficiency can lead to:
- AOsteoporosis
- BOsteomalacia
- CRickets
22Severe VITAMIN D deficiency can lead to Osteomalacia/Rickets. Are they the same thing?
- AYeah
- BNah
23Which of the following helps to maintain normal balance between bone formation and resorption:
- AAndrogens
- BOestrogens
- CBoth of the above
- DNeither of the above
24True or False: Oestrogens help to keep bone cells alive.
- ATrue
- BFalse
25True or False: Androgens help to keep bone cells alive.
- ATrue
- BFalse
26True or false: Anorexia leads to weak bones solely through nutrient deficiency.
- ATrue
- BFalse
27Glucocorticoids (Cortisone etc) are catabolic at pharmacologic doses. Where does each manifestation occur?
↓ Calcium absorption in the [blank_start]__________[blank_end];
↑ Calcium losses in the [blank_start]__________[blank_end];
↓ IGF-1 in the [blank_start]__________[blank_end];- AGut
- BKidney
- CBone
28Protein intake helps:
- ABone function
- BMuscle function
- CBoth of the above
- DNeither of the above
29If a diet contains inadequate Calcium to replace urinary losses, what happens?
- ARaid bones for Calcium
- BNothing
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- PHSI3011 05-2 Maintenance of Bone Health
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- Created on 8 Nov 2017 · updated on 10 Nov 2017
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