Flashcards
Cell Cycle I
Cards in this deck (26)
- 1Cell cycleG1,S,G2,M phase
- 2M phase1. Mitosis
2. Cytokinesis - 3interphaseG1,G2,S
- 4G2 of interphaseChromosomes start to condense
- 5ProphaseChromosomes condensed visible
Centrosomes duplicate
Begin to move to opposite poles of the cell - 6PrometaphaseFragmentation of n. envelope membranes
Centrosomes move to complete their migration
Breakdown of n. envelope allows spindle MT to make contact w/ chromo
Attaches at centromere, an are of heterochromatin w/ CEN sequence
KC MT attach to centromere KC - 7MetaphaseMaximally condensed chromosomes align along metaphase plate
- 8Anaphase AChromosomes pulled centromere first towards spindle poles as KC MT shorten
- 9Anaphase BSpindle poles move away from each other as interpolar MT lengthen
- 10TelophaseChromosomes reach pole of cell
decondense
nucleoli develop
n. envelope reforms
Spindle disassembles - 11CondensationCondensins, heterodimers that carry out final chromosome condensation
- 12MOALoop fastener
Orientated gyre - 13What holds chromosomes together?Cohesins
- 14Sets of MT in spindleAstral MT
Kinetochore MT
Interpolar MT - 15Astral MTBind to PCM, afix spindle
Mediated by - 16Kitechore MTAffix to chromosomes
- 17Interpolar MTAffix to other MT of the spindle apparatus
via protein cross-links - 18DynesinAttaches astral MT to PCM
- 19Kinesin-14Tightens spindle
- 20Kinesin-5Expands spindle
- 21Kinesin-4/-10Move chromosomes to poles of MT
- 22CentromereAre of heterochromatin with CEN sequence.
- 23Role of kinetochoresDNA has little affinity for mitotic spindle
Kinetochores facilitate fastening of DNA to spindle MT - 24Kinetochore layersCheckpoint: Collar - attaches to spindle
Outer: Structural
Inner: Binds to centromere - 25What orientates the chromosomes?Kinesis-4/-10
- 26Chromatid separation MOA (3)During anaphase,
MT tubuluin removed from + and - ends to shorten the spindle.
Depolymerisation of + end of kinetochore MT.
Pulls KC to pole, separase removes cohesin.
Information
- Description
- User has deleted their subject information Flashcards on Cell Cycle I, created by Deleted user on 12/04/2018.
- Created by
- Deleted user · Apr 2018
- Updated
- Apr 12, 2018
- Views
- 8
- History
-
- Created by J yadonknow · Apr 4, 2018
- Copied by J yadonknow · Apr 12, 2018
- Rating