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L31 Type 2 DM

Deleted user 7 questions Updated 26 May 2019

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Questions in this quiz (7)

  1. 1Diabetes Mellitus is a metabolic disorder resulting from high concentrations of blood glucose.
    Glucose remains in the
    blood, therefore:
    • [blank_start]Increased[blank_end] urination
    • Thirsty
    • Weight [blank_start]loss[blank_end]
    • Tired
    • [blank_start]Poor[blank_end] circulation
    1. AIncreased
    2. BDecreased
    3. Closs
    4. Dgain
    5. EPoor
    6. FGood
  2. 2T2DM is due to insulin deficiency (Beta islet cell dysfunction & cell loss up to 50% at diagnosis), and insulin resistance.
    1. ATrue
    2. BFalse
  3. 3Metabolic syndrome is associated with excess nutrition, insufficient [blank_start]exercise[blank_end] and a genetic predisposition. It is characterised by chronic [blank_start]inflammation[blank_end] in the adipose tissue, liver, pancreas, and vasculature.
    • Doubles the risk of [blank_start]atherosclerotic[blank_end] heart disease
    • Doubles risk of stroke
    • Five times the risk of [blank_start]diabetes[blank_end]
    • Increased risk of venous thrombosis
    1. Aexercise
    2. Binflammation
    3. Cdiabetes
    4. Datherosclerotic
  4. 4HbA1c is glycosylated haemoglobin. It can be used to determine plasma [blank_start]glucose[blank_end] over the previous 8-12 [blank_start]weeks[blank_end] and so [blank_start]monitor[blank_end] diabetic control or [blank_start]diagnose[blank_end] diabetes. The more glucose in the blood, the more haemoglobin is [blank_start]glycosylated[blank_end].
    1. Aglucose
    2. Bweeks
    3. Cmonitor
    4. Ddiagnose
    5. Eglycosylated
  5. 5The lifetime risk of a child with 1 parent with T2D is 40%, and increases to 70% if both parents have/had T2D.
    1. ATrue
    2. BFalse
  6. 6Type 2 Diabetes - Pathogenesis:
    • Insulin resistance begins many [blank_start]years[blank_end] before onset of T2D
    • When insulin [blank_start]secretion[blank_end] can not overcome [blank_start]resistance[blank_end]: hyperglycaemia and T2D
    • Typically [blank_start]half[blank_end] of B islet cells left at diagnosis
    • Abnormalities in other hormones (increased [blank_start]glucagon[blank_end]) & impaired responses to others (egg GLP-1)
    • Changes in gut [blank_start]microbiota[blank_end]
    • Inflammation
    1. Ayears
    2. Bsecretion
    3. Cresistance
    4. Dhalf
    5. Eglucagon
    6. Fmicrobiota
  7. 7Pathophysiology of T2DM:
    - Macrovascular (50% of patients): [blank_start]cardiovascular disease[blank_end], develops earlier and is more severe
    - Microvascular (~27% patients): [blank_start]kidney, retina and the nervous system[blank_end]
    - Co-morbidities: non-alcoholic [blank_start]fatty liver[blank_end] disease, obstructive sleep [blank_start]apnoea[blank_end] and depression
    1. Acardiovascular disease
    2. Bkidney, retina and the nervous system
    3. Cfatty liver
    4. Dapnoea

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Description
User has deleted their subject information Quiz on L31 Type 2 DM, created by Deleted user on 16/04/2019.
Author
Deleted user
Language
English
Views
46
History
Created on 16 Apr 2019 · updated on 26 May 2019
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