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L34.5 CKD and AKI
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Questions in this quiz (7)
1Choose the incorrect statement about Acute Kidney Injury (AKI).
- AIt is an abrupt decrease in kidney function that occurs over a period of 7 days or less
- BIt is stimated to occur in approximately 50% of patients admitted to the intensive care unit (ICU)
- CIt can predispose you to CKD
- DCKD patients cannot get AKI
2Choose the incorrect statement about chronic kidney disease (CKD)
- AIt is abnormalities in kidney structure or function that persist for >90 days
- BIt presents a high economic burden
- CAt least as many deaths are attributable to kidney disease as to cancer, diabetes or respiratory diseases
- DRisk factors for AKI and CKD, such as advanced age, diabetes and hypertension, often overlap.
- EAKI and CKD are discrete and separate conditions.
3NZ has higher rates of sepsis, post infectious glomerulonephritis and HUS causing AKI compared with other countries in the developed world.
- ATrue
- BFalse
4Reduced renal blood flow ([blank_start]ischemia[blank_end]) initiates AKI. It can be as a result of infection ([blank_start]sepsis[blank_end]), medications, disease, or trauma. The medication combination likely to cause AKI is the ‘triple whammy’; concurrent use of an [blank_start]ACE[blank_end] inhibitor or an ARB, with a [blank_start]diuretic and an NSAID[blank_end].
AKI is largely [blank_start]asymptomatic[blank_end] and late diagnosis of injury is common.- Aischemia
- Bsepsis
- Cdiuretic and an NSAID
- DACE
- Easymptomatic
5Pathogenesis of AKI:
1. Disruptions of the glycocalyx and [blank_start]endothelial[blank_end] monolayer in renal tubule
2. Upregulation of [blank_start]adhesion[blank_end] molecules
3. Enhanced [blank_start]leukocyte-endothelium[blank_end] interactions
4. Formation of [blank_start]microthrombi[blank_end]
5. Inflammation causing [blank_start]fluid[blank_end] overload, [blank_start]electrolyte[blank_end] imbalances- Aendothelial
- Badhesion
- Cleukocyte-endothelium
- Dmicrothrombi
- Efluid
- Felectrolyte
6CKD Pathogenesis"
1. Nephrons atrophy with time
2. Worsened by genetic & environmental factors – [blank_start]hypertrophy[blank_end]
3. Fewer nephrons cause an increase in [blank_start]nephron[blank_end] size, [blank_start]podocytes[blank_end] can’t cope & detach – loss of barrier function and impaired filtration - [blank_start]proteinuria[blank_end]
4. Inflammation, which leads to fibrosis & [blank_start]scar[blank_end] formation
5. Leads to [blank_start]ischaemia[blank_end]- Ahypertrophy
- Bnephron
- Cpodocytes
- Dproteinuria
- Escar
- Fischaemia
7Which of these is not a systemic effect of CKD?
- AFluid & electrolyte imbalances
- BAnaemia
- CMineral bone disorder – bone pain, fractures, deformities
- DMetabolic acidosis – muscle wasting, bone demineralisation
- EHyperuricaemia – systemic inflammation, neurological changes
- FPruritis
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- User has deleted their subject information Quiz on L34.5 CKD and AKI, created by Deleted user on 16/04/2019.
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- Deleted user
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- English
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- Created on 16 Apr 2019 · updated on 26 May 2019
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