Phases of Wound Healing

Phases of Wound Healing

1. Haemostasis

   • AIM: prevent further bleeding by creating blood clots
   • Vessel constriction --> Platelet plug --> Fibrin plug

2. Acute Inflammation

   • Neutrophils + Macrophages remove debris from injury
   • Clinical signs of inflammation present

3. Proliferation

   • Granulation tissue formation + Replacement of epithelial cells
   • Macrophages produce growth factors --> proliferation of epithelial cells + fibroblasts
   • Restores normal function & structure

4. Wound Maturation & Remodelling

   • When inflammation has finished & new tissue has formed
   • Granulation tissue is replaced by mature connective tissue