Endocrinology - created from Mind Map

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Intracellular communication

Hormones

3 classes of hormones

Gap Junctions

Synaptic

Paracrine and autocrine

Endocrine

Message transmitted from cell to cell

Specificity depends on anatomical location

Message transmitted across synaptic cleft

Specificity depends on anatomical location + receptos

Message transmitted by diffusion in interstitial fluid

specificity depends on receptors

Message transmited by circulating body fluids

Depends on receptor

High affinity

Synergistic

Permissive

Antagonistic

Competitive

Hormones efffective at low concs.

Effect of two hormones > than one

presence of one hormone necessary for another to have effect

Two hormones oppose each others effect

e.g. inslulin vs glucagon

Two hormones similar in structure compete for same receptor

Steroids : cholesterol

Peptides: amino acids

Amino acids: tyrosine