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Endo test
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Questions in this quiz (69)
1What are the 7 Hormones secreted from the Anterior Pituitary?
- ATH
- BFSH
- COxytocin
- DProlactin
- EACTH
- FACTH Like Hormone
- GGrowth Hormone
- HLH
- IADH
2Hypoglycemia decreases secretion
- ATrue
- BFalse
3TH is synthesized by thyriotrophs
- ATrue
- BFalse
4All hormones in the pituitary are released by secretory granules
- ATrue
- BFalse
5LH causes spermatogensis in males and follicle development in females
- ATrue
- BFalse
6Secretion regulation for TH
- ATRH
- BInhibin
- CSomatostatin
- DGHRH
7GnRH is a sigmodial curve
- ATrue
- BFalse
8Small amounts of LH release will causes little to no response because
- ANot enough receptors are occupied to give response
- BResponse under a certain level are insignificant
- CAll the receptors are occupied and therefore can't give a response
9Slow rising GnRH pulses give the best response in LH release
- ATrue
- BFalse
10Why does square waves of GnRH give the best LH release?
- AThe receptors have become desensitized to the Hormone
- BIt looks like a continuous signal
- CThere is a delay in signal and cells are less desensitized
11Continuous low levels are GnRH release causes no effect
- ATrue
- BFalse
12Continuous GnRH stimulation causes a faster increase then slow decrease of LH
- ATrue
- BFalse
13What does the supramaximal response show in the GnRH vs LH release graph
- AContinues to increase
- BThere is an extra response to a high concentration because the cell receptors have become less desensitzed
- CThere is no change because even with an increase in GnRH the cell is still desensitized
14How does an increase in time effect the supramaximal response?
- AThe longer the time the less GnRH released
- BShorter time gives the best supramaximal response
15ACTH has only one release system
- ATrue
- BFalse
16Growth Hormone is diurnal becuase
- AHigh during the day, low at night
- BEqual for day and night
- CLow during the day, and high at night
- DOnly found at night
17Where is IGF produced?
- AHypothalamus
- BPancreas
- CLiver
- DAdrenal Glands
18What is needed for GH to be released?
- AGH is always there
- BGHRH
19Continuous levels of GnRH are need
- ATrue
- BFalse
20What stimulates IGF-1 secretion?
- ALH
- BGH
- CFSH
- DTH
21What is IGF-!'s function?
- ADirectly inhibits GH
- BIndirectly inhibits GH
- CDirectly stimulates GH
- DIndirectly stimulates GH
22What cell type does IGF-! suppress?
- AThyrotrophs
- BSomatotrophs
- CAdrenotrophs
23Which answer doesn't IGF-! indirectly inhibit GH?
- ASuppresses Somatotrophs
- BSuppresses GHRH release
- Cinhibits somatostatin
- DShort-loop feedback
24There is only 1 GH peak during period
- ATrue
- BFalse
25What is the LH at M-10?
- ALow in the blood because of peaks overlapping
- BHigh in the blood because of peaks overlapping
- CHigh in the blood because of peaks not overlapping
- DLow in the blood because of peaks not overlapping
26There are higher LH released after the period?
- ATrue
- BFalse
27Which hormone has the fastest decay over time?
- ALH
- BGH
28which hormone has a faster rise rate over time?
- AGH
- BLH
29What does an increase in Estrogen do to GH?
- ADecreases GH basal level
- BIncreases GH basal Level
30Why is there high level of GH in females than males
- APulses are shorter and more prolonged
- BFrequency of amplitude is higher in females
- Clarger pulses and more prolonged
- DFrequency of amplitude is lower in females
31Which age/sex has the highest GH level in the blood?
- AYoung girls
- Byoung adults
- Cfetus
- Dlate prepubertal boys
32Which is more important for GH release at night?
- ASleep
- BDarkness
33What two forms does GHRH in the hypothalamus
- A40 AA
- B41AA
- C45AA
- D44 AA
34What is GHIH other name?
- ASomatostatin
- BSecretin
- CInhibiton
- DGrowth Hormone inhibitor
35The N terminal on the the hormone is used to show species differences.
- ATrue
- BFalse
36What does GHRH not do?
- AIncrease Secretion of GH
- Bincrease GH biosynthesis
- CIncrease GH transcription
- Dincrease GH due to hyperglycemia
37What is arachidonic acid a precursor for?
- AProstaglandins
- BTestosterone
- CEstrogen
- DGH
38What type of receptors does GHRH bind to?
- AGTP- linked receptors
- BATP-linked receptors
39Which 2nd messenger pathway is not activated by GHRH binding?
- AcGMP
- BCa2+-
- CIP3- DAG
- DArachidonic acid
40Aromatic ring GH releasing peptides are the most active
- ATrue
- BFalse
41GH releasing peptides are synthesized based on Leu- enkephalin
- ATrue
- BFalse
42Why is the pituitary sensitive to GHRH depending on maturity?
- AAdults are most sensitive because GH is less important
- BFetus is most sensitive because GH is less important
43How many membrane spanning domains does the GHRH receptor span?
- A5
- B6
- C7
- D8
44There is a direct correlation of GH and maturity
- ATrue
- BFalse
45What is the function of Pit-1 (pituitary-specific transcription factor)?
- AInhibits GH and GHRH transcription
- BActivates GH and GHRH transcription
- CInhibits GH and GHRH translation
- DActivates GH and GHRH translation
46Somatostatin is mostly synthesized in ___________ of pancreatic islet, brain regions and gut
- Aalpha cells
- Bbeta cells
- CDelta cells
- Dgamma cells
47How does somatostatin get released?
- AK+ induced membrane depolarization
- BCa2+ induced membrane depolarization
- CNa2+ induced membrane depolarization
- DCl- induced membrane depolarization
48SS is only produced in one tissue type
- ATrue
- BFalse
49SS is produced in secretory tumours
- ATrue
- BFalse
50How many cytokine receptors on the GH receptor
- A1
- B2
- C3
- D4
51GH receptor has a second messenger system because..
- AIt doesn't interact with G proteins
- BIt doesn't bind long enough to the receptor
52How many receptors does GH bind to to cause dimerization?
- A1
- B2
- C4
- D6
53GHR is bound between GHR associated JAK2 tyrosine kinase.
- ATrue
- BFalse
54Which proteins area phospholated by tyrosyl
- AJAK2
- BGHR
- CTRH
- DGHRH
55Name two other signalling that GH activates?
- AMAP kinases
- BInsulin receptor substances
- CcAMP
56What is not part of the changes caused my GH?
- AIncrease in transport proteins
- BIncrease in enzymatic function
- CIncrease in gene expression
- DIncrease in GHRH release
57What is not caused by a burst of GH?
- AIncreased receptors
- BRapid increase in serum GHBP
- CChange in clearance peak
- DDecrease receptor endocytosis
58What are neurolipids produced from?
- ATestosterone
- BCholesterol
59Steroid hormones are hydrophilic because they are lipid soluble
- ATrue
- BFalse
60Why is cholesterol continuously broken down?
- ATo use
- BTo excrete
61Which two ways does the cell get cholesterol?
- AUptake as LDL's from the blood
- BProduce from Acetyl-CoA
- CProduced by transcription
62Where does the conversion of cholesterol to other steroids occur?
- ANucleus
- BMitochondria
- CER
- DGolgi Apparatus
63Pregnenolone - 17 a Pregnenolone- dehydroiandrosterone is part which pathway?
- ADelta 5
- BDelta 4
64Which area is progesterone important?
- ALuteal cells in woman
- BStroma cells in woman
- CLeydig cells in men
- DStroma cells in men
65What does the ovary secrete?
- Aandrostenedione
- Bdehydroepiandrostenedione
- Ctestosterone
- D17 B estradiol
66What chemical structure differs in estrogen compared to other steroid hormones?
- ABenzene ring
- BLong carbon chains
- CAromatic rings
- DOH's
67All amine hormones are derived from tyrosine
- ATrue
- BFalse
68Amines are lipophilic or lipophobic
- A lipophilic
- Blipophobic
69Catecholamine's are not water soluble
- ATrue
- BFalse
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- Quiz on Endo test , created by Alexandra McCabe on 19/05/2015.
- Author
- Alexandra McCabe
- Language
- English
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