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Infectious Diseases Final MCQs- 5th Year PMU
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Questions in this quiz (92)
1The specific CNS complication of Chickenpox is
- Acerebellitis
- Bmeningitis serosa
- Cpolyradiculoneuritis - Guillain-Barre
2Treatment of cerebral oedema includes
- ADiuretics – spironolactone
- BDiuretics – mannitol, furanthril
- CNon-steroidal anti-inflammatory drugs
3Common presentations of AIDS are
- Aprolong morning low grade fever, weight loss, diarrhea
- Bhyperpyrexia with profuse sweating, dehydration with metabolic changes
- Cbulimia, hyperactivity, psychomotor agitation
4Which meningitis is characterized by the following CSF findings – lymphocytic pleocytosis, normal or slightly elevated protein and normal glucose level?
- AViral
- BPurulent
- CTuberculous
5The rash in Scarlet fever is
- Amaculo-papules, vesicular, different stages at the same time
- Bvesicular rash, which most commonly affects a thoracic dermatome
- Cpustular, at the same stage of development, deep-seated, firm, round, well-circumscribed
6Typical for Diptheria are
- Adense, dirty gray, hard deposits on the tonsils
- Bwhitish deposits on the tonsils and buccal mucosa, easily removable
- Cthe disease is widespread in Bulgaria
7The most common clinical manifestation of Salmonellosis is
- Asepsis
- Bcholecystitis
- Cgastroenteritis
8Which is the antibiotic of choice of for Mediterranean spotted fever
- AGentamycin
- BDoxycycline
- CCeftriaxone
9Poliomyelitis is characterised by
- Aflaccid asymmetric, proximal paralysis
- Bflaccid symmetric, proximal paralysis
- Cfull recovery of the affected limb
10Typical for clinical presentation of Cholera is
- Arigor and high fever
- B‘rice water’ stools
- Cpersistent vomiting, severe stomach pain
11The agent of which disease has teratogenic effect?
- ARubella
- BScarlet fever
- CMeasles
12The main factor for chronicity in HBV infection is
- Aage
- Binnate immunity
- Cgender
13The diarrheal syndrome in shigellosis is characterised with
- Alarge amount of watery stools + abdominal pain
- Bsparse, bloody mucoid stools + tenesmi
- Cvoluminous liquid, ” rice water” type stools
14Hepatitis with the most severe course with possibility of acute liver failure is
- Aacute hepatitis C
- Bacute hepatitis B+ hepatitis D
- Cviral hepatitis E
- Dviral hepatitis A
15Which infection is vaccine preventable
- ASalmonella
- BMeasles
- CScarlet fever
16Hypopotassemia may be suspected in a patient with
- Aenhanced motility and spastic colon
- Bintestinal paresis and bloated abdomen
- Cgeneralized seizures
17Empirical therapy for bacterial meningitis includes
- A3rd generation Cephalosporins + Vancomycin
- BPenicillin + Metronidazole
- C3rd generation Cephalosporins + Clindamycin
18Measles rash appears
- A24 h after onset of the disease
- Bthe disease begins with it
- Con 3-5-the day of disease onset
19The stools in cholera resemble
- Arice water
- Bsputum with mucus, blood and pus
- Craspberry jelly
20The most common causative agents of purulent meningitis are
- AS.pneumoniae, N. meningitidis, H. influenzae
- BS.pneumoniae, Staph.aureus, Myc. tuberculosis
- CN meningitidis, L. monocytogenes, St. epidermidis
21The rash of Chicken pox is
- Amaculo-papules, vesicular, different stages at the same time
- Bvesicular rash, which most commonly affects a thoracic dermatome
- Cpustular, at the same stage of development, deep-seated, firm, round, well-circumscribed
22Who is NOT at risk for severe Chickenpox
- Apersons with cellular immunodeficiency
- Bpregnant
- Cchildren aged 2-6
23The earliest laboratory test for confirmation of acute hepatitis C is
- AAnti-HCV by ELISA
- BHCV RNA by PCR
- CHCV Ag by ELISA
24Pregnant in the 1st trimester has discrete macular rash and negative serological test (ELISA) for Rubella. What is the next step?
- ATherapeutic abortion
- BRibavirin therapy
- CRepeating the test after 3 weeks
25Shigellosis is likely to present with seizures in
- Aelderly people
- Bchildren under the age of 3 years
- Csuch onset is unlikely
26Which test is best to confirm EBV as causative agent of infectious mononucleosis
- Adetection of heterophile antibodies
- Bdetection of specific antibodies to EBV
- Cdetection of nucleic acid of EBV in the blood
27Raspberry tongue is typical for
- AScarlet fever
- BMeasles
- CChickenpox
28The most common neoplasm in HIV infection is
- AKaposki‘s sarcoma
- BPulmonary carcinoma
- CMelanoma
29The aminotransferases (ALT and AST) in acute viral hepatitis are
- ANormal
- B100 E/L
- C> 1000 E/l
30Etiological treatment of choice in cholera is
- Apenicillin
- Bcephalosporin 4-th generation
- Ctetracycline
31Antibiotic of choice for the treatment of Scarlet fever is
- Atetracycline
- Bpenicillin / beta-lactam
- Cgentamicin
32Meningeal irritation includes
- Anuchal rigidity, hyperesthesia
- Bdiminished tendon reflexes
- Caltered mental status
33Route of transmission in Lyme disease is
- Avia tick bite
- Bvia drinking unpasteurized milk
- Cvia mosquito bites
34The most common causative agent of pneumonia in AIDS patients is
- AMycoplasma pneumoniae
- BPneumocystis jiroveci (carinii)
- CHantavirus
35Typical clinical manifestation of tetanus is
- Aconfusion
- Bperiodic muscle rigidity
- Cpermanent muscle rigidity and periodic seizures
36Antibiotic of choice for treatment of Erythema migrans is
- ACefrtiaxone
- BDoxycycline
- CGentamycine
37Measles rash
- Aappears after 24 h after the disease onset
- Bthe disease starts with it
- Cappears on 3-5th day of disease onset
38At risk of acute viral hepatitis C are
- Aintravenous drug abusers
- Bnewborns in poor sanitary conditions
- Ctravellers to tropical countries
39The rash of meningococcemia is
- Ahemorrhagic necrotic, localized predominantly on the lower limbs and buttocks
- Bvesicular, diffuse
- Cvesicular, highly pruritic
40Initial treatment of infectious diarrhea includes
- Arehydration
- Bantibiotic
- Ccorrection of ↓K
41On suspicion of acute viral hepatitis the minimum laboratory TESTS are
- Aalkaline phosphate, gamma glutamyl transferase
- Burine (bile pigments), serum (ALT and AST, bilirubin)
- Ccomplete blood count, electrolytes, acid-base metabolism
42The evolution of Chickenpox rash is
- Amacula – papule - vesicle - crust
- Bmacula- papule - brown pigmentation
- Cpetechiae- ecchymosis- suffusion
43The main factor for chronicity in HBV infection is
- Aage
- Binnate immunity
- Cgender
44The mainstay of diphtheria treatment is
- Aantibiotics
- Bantitoxin serum
- Ccorticosteroids
45Which infection is vaccine-preventable
- AMeasles
- BScarlet fever
- CLyme borreliosis
46 Koplik spots are pathognomonic sign for
- AScarlet fever
- BMeasles
- CRubella
47Jaundice as a clinical manifestation of acute viral hepatitis C is seen
- Ain a few patients
- Bin the majority of patients
- Cin about half of the cases
48Laboratory minimum for suspected viral hepatitis is
- Aurine (bile pigments), serum (ALT and AST, bilirubin)
- BCBC, electrolytes, acid-base balance
- Cabdominal ultrasound
49Meningeal irritation, prolonged clouding consciousness and focal neurological findings are common in
- Ameningoencephalitis
- Bencephalitis
- Cmeningitis
50The incubation period in Shigellosis is
- A2 weeks
- B1-7 days
- C4-6 hours
51What type of toxin is released by Salmonella bacteria on cell lysis
- Aendotoxin
- Bneurotoxin
- Centerotoxin
52Which of the following agents causes hemolytic-uremic syndrome
- Aenterohemorrhagic E.coli
- Benteroinvasive E.coli
- Cpathogenic E.coli
53The agent of which disease has teratogenic effect?
- ARubella
- BScarlet fever
- CMeasles
54Which of the following statements regarding enteroviruses as causative agents of aseptic meningitis are NOT TRUE?
- AEnteroviruses account for up to 80% of cases of viral meningitis.in children
- Bthe clinical presentation in children is milder than in adults
- Clymphocytes are predominant in the first 24 hours, later neutrophils prevail
55Which type of immunity is impaired in HIV infection?
- Ahumoral
- Bcell mediated
- Cinnate
56Viral hepatitis A is transmitted via
- Afecal-oral mechanism
- Bparenteral mechanism
- Csexual mechanism
57The most common causative agent of of Infectious mononucleosis is
- AEpstein-Barr virus
- BCytomegalovirus
- CHIV
58The main route of transmission of hepatitis C virus is
- Afecal-oral
- Bintravenous usage
- Csexual
59The rash in Scarlet fever is ???
- Amaculo-papules, vesicular, fast evolution of stages
- Bvesicular rash, which most commonly affects a thoracic dermatome
- Cpustular, at the same stage of development, deep-seated, firm, round, well-circumscribed
60The mental status in tetanus is
- Ablurred
- Balert
- Challucinations are typical
61Typical Measles rash is
- Amaculo-papular rash appearing on the first day of the disease
- Bmaculo-papular rash, confluent, appears on the 4-5 the day
- Cdiscrete maculo-papular rash fades after 3 days
62Which type of meningitis is characterized by the following CSF findings – lymphocytic pleocytosis, elevated protein and decreased glucose level
- Aviral
- Bpurulent
- Ctuberculous
63Which of the following conditions are NOT AIDS-defining illness?
- AHerpes zoster
- BKaposki’s sarcoma
- CEsophageal candidiasis
64Cholera initially presents with
- Achills and high fever
- Bdiarrhea ” rice water” type
- Cintractable vomiting
65Which of the following microorganisms is associated with diarrhoea after antibiotic therapy or severe operations
- ACl. difficile
- BSalmonella
- CE.coli
66Diarrheal syndrome in shigellosis is characterised by
- Alarge amount of watery stools + abdominal pain
- Bsparse, bloody mucoid stools + tenesmi
- Cvoluminous liquid, ” rice water” type stools
67A pregnant woman in first trimester had contact with a sick child, suspected to have rubella. How could you manage her
- Ato clarify if the child has Rubella
- Bto recommend abortion on medical grounds
- Cto determine her immunity by serology
68The most common presentation of Lyme borreliosis is
- Aerythema migrans
- Barthritis
- Cneuritis
69The most common initial complaints in acute viral hepatitis are
- Afatigue, anorexia, nausea, loss of appetite
- Bsevere abdominal pain radiating to the shoulders and vomiting
- Cfever and diarrhoea
70First choice antibiotic for treatment of pertussis is
- Aceftriaxone
- Bmacrolides
- Camikacin
71Empirical treatment on suspicion of bacterial meningitis includes
- A3rd generation Cephalosporins + Vancomycin
- BPenicillin + Metronidazole
- C3rd generation Cephalosporins + Clindamycin
72Thick pseudomembrans, spreading across the pharyngeal mucosa and bleeding while dislodging, are characteristic for
- Amononucleosis
- Bdiphtheria
- Cstrepto pharyngitis
73Pustula maligna is typical for
- AAnthrax
- BMediterranean spotted fever
- CTularemia
74Anthrax infection results from
- Aexposure to cattle and goats
- Btick bite
- Cmosquito bite
75Acute hepatitis C becomes chronic in
- A30-80%
- B< 2%
- C>90%
76The stages in the course of HIV/AIDS infection are
- Aearly HIV infection, latency period, AIDS
- Bcatarrhal period , rash period , convalescent period
- Cinitial intoxication period, period of generalized lymphnodulomegaly, period of hepatosplenomegaly
77Serological markers of acute viral hepatitis B are
- AHBsAg (+) and anti HBc IgM (+)
- BHBsAg (+) and anti HBc total (+)
- Canti HBsAg (+) and anti HAV IgM (+)
78Arthralgia in acute viral hepatitis presents with
- Ajoint pain without swelling and redness
- Bswelling, redness and forced position
- Cswelling without pain and redness
79Tache noire (black spot) at the site of the tick bite represents
- Apainless ulcer covered with black (necrotic) crust
- Bpainless oval or round pink or red skin plaque> 5 cm
- Cpainful hot red plaque with raised edges
80Which of the following findings IS NOT characteristic of infant meningitis?
- Abulging fontanelle, Lessage sign
- Bdistended abdomen
- Ccrie encephalique
81The screening test for HIV infection is
- Aanti HIV (ELISA)
- Bviral RNA (PCR)
- Canti HIV (immunoblot)
82The rash in Mediterranean spotted fever is
- Amaculopapular
- Bvesicular
- Cerythematous
83Which diseases in not vaccine preventable
- ALyme borreliosis
- BPoliomyelitis
- CMeasles
84The most common electrolyte abnormalities in patients with diarrhea are
- Ahyponatremia and hypokaliemia
- Bhypercalcemia and hyperkaliemia
- Chypernatriemia and hyperchloremia
85Acyclovir is recommended to which of following cases
- AChicken pox - mandatory
- BChicken pox in immunocompromised patients
- CKaposi sarcoma
86Which of the following statements regarding leptospirosis IS NOT true”
- ALeptospirosis is a biphasic illness with multiorgan involvement
- BGentamycin is the antibiotic of choice
- CInfection is acquired during walking or bathing in rivers
87At risk for development of Herpes Zoster are
- Aadolescents (aged 11-19 years)
- Bpatients with HIV infection
- Cnewborns
88Characteristic clinical manifestation of enteroviral infections is
- AHerpagina
- BGingivostomatitis
- CExudative pharyngitis
89The rash in Scarlet fever is
- Asmall maculopapules predominantly in the axilar and inguinal regions
- Bvesicular rash, which most commonly affects a thoracic dermatome
- Cpustular, at the same stage of development, deep-seated, firm, round, well-circumscribe
90Inflammatory diarrhea is commonly caused by
- AShigella sp., Campylobacter jejuni, Cl. difficile
- BViruses, enterotoxigenic E. coli
- CS. aureus, B. cereus, most Salmonella sp.
91When is ART warranted
- AFor all HIV positive regardless of CD4 count
- BCD4<200 cells/µL
- CCD4< 350 cells/µL
92In the case of infectious mononucleosis-like symptoms, it is important to consider
- Aprimary HIV infection
- Bneoplasms
- Csyphilis
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- Infectious Diseases Final MCQs- 5th Year PMU
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