Infectious Diseases Final MCQs- 5th Year PMU

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Infectious Diseases Final MCQs- 5th Year PMU
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Resumen del Recurso

Pregunta 1

Pregunta
The specific CNS complication of Chickenpox is
Respuesta
  • cerebellitis
  • meningitis serosa
  • polyradiculoneuritis - Guillain-Barre

Pregunta 2

Pregunta
Treatment of cerebral oedema includes
Respuesta
  • Diuretics – spironolactone
  • Diuretics – mannitol, furanthril
  • Non-steroidal anti-inflammatory drugs

Pregunta 3

Pregunta
Common presentations of AIDS are
Respuesta
  • prolong morning low grade fever, weight loss, diarrhea
  • hyperpyrexia with profuse sweating, dehydration with metabolic changes
  • bulimia, hyperactivity, psychomotor agitation

Pregunta 4

Pregunta
Which meningitis is characterized by the following CSF findings – lymphocytic pleocytosis, normal or slightly elevated protein and normal glucose level?
Respuesta
  • Viral
  • Purulent
  • Tuberculous

Pregunta 5

Pregunta
The rash in Scarlet fever is
Respuesta
  • maculo-papules, vesicular, different stages at the same time
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribed

Pregunta 6

Pregunta
Typical for Diptheria are
Respuesta
  • dense, dirty gray, hard deposits on the tonsils
  • whitish deposits on the tonsils and buccal mucosa, easily removable
  • the disease is widespread in Bulgaria

Pregunta 7

Pregunta
The most common clinical manifestation of Salmonellosis is
Respuesta
  • sepsis
  • cholecystitis
  • gastroenteritis

Pregunta 8

Pregunta
Which is the antibiotic of choice of for Mediterranean spotted fever
Respuesta
  • Gentamycin
  • Doxycycline
  • Ceftriaxone

Pregunta 9

Pregunta
Poliomyelitis is characterised by
Respuesta
  • flaccid asymmetric, proximal paralysis
  • flaccid symmetric, proximal paralysis
  • full recovery of the affected limb

Pregunta 10

Pregunta
Typical for clinical presentation of Cholera is
Respuesta
  • rigor and high fever
  • ‘rice water’ stools
  • persistent vomiting, severe stomach pain

Pregunta 11

Pregunta
The agent of which disease has teratogenic effect?
Respuesta
  • Rubella
  • Scarlet fever
  • Measles

Pregunta 12

Pregunta
The main factor for chronicity in HBV infection is
Respuesta
  • age
  • innate immunity
  • gender

Pregunta 13

Pregunta
The diarrheal syndrome in shigellosis is characterised with
Respuesta
  • large amount of watery stools + abdominal pain
  • sparse, bloody mucoid stools + tenesmi
  • voluminous liquid, ” rice water” type stools

Pregunta 14

Pregunta
Hepatitis with the most severe course with possibility of acute liver failure is
Respuesta
  • acute hepatitis C
  • acute hepatitis B+ hepatitis D
  • viral hepatitis E
  • viral hepatitis A

Pregunta 15

Pregunta
Which infection is vaccine preventable
Respuesta
  • Salmonella
  • Measles
  • Scarlet fever

Pregunta 16

Pregunta
Hypopotassemia may be suspected in a patient with
Respuesta
  • enhanced motility and spastic colon
  • intestinal paresis and bloated abdomen
  • generalized seizures

Pregunta 17

Pregunta
Empirical therapy for bacterial meningitis includes
Respuesta
  • 3rd generation Cephalosporins + Vancomycin
  • Penicillin + Metronidazole
  • 3rd generation Cephalosporins + Clindamycin

Pregunta 18

Pregunta
Measles rash appears
Respuesta
  • 24 h after onset of the disease
  • the disease begins with it
  • on 3-5-the day of disease onset

Pregunta 19

Pregunta
The stools in cholera resemble
Respuesta
  • rice water
  • sputum with mucus, blood and pus
  • raspberry jelly

Pregunta 20

Pregunta
The most common causative agents of purulent meningitis are
Respuesta
  • S.pneumoniae, N. meningitidis, H. influenzae
  • S.pneumoniae, Staph.aureus, Myc. tuberculosis
  • N meningitidis, L. monocytogenes, St. epidermidis

Pregunta 21

Pregunta
The rash of Chicken pox is
Respuesta
  • maculo-papules, vesicular, different stages at the same time
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribed

Pregunta 22

Pregunta
Who is NOT at risk for severe Chickenpox
Respuesta
  • persons with cellular immunodeficiency
  • pregnant
  • children aged 2-6

Pregunta 23

Pregunta
The earliest laboratory test for confirmation of acute hepatitis C is
Respuesta
  • Anti-HCV by ELISA
  • HCV RNA by PCR
  • HCV Ag by ELISA

Pregunta 24

Pregunta
Pregnant in the 1st trimester has discrete macular rash and negative serological test (ELISA) for Rubella. What is the next step?
Respuesta
  • Therapeutic abortion
  • Ribavirin therapy
  • Repeating the test after 3 weeks

Pregunta 25

Pregunta
Shigellosis is likely to present with seizures in
Respuesta
  • elderly people
  • children under the age of 3 years
  • such onset is unlikely

Pregunta 26

Pregunta
Which test is best to confirm EBV as causative agent of infectious mononucleosis
Respuesta
  • detection of heterophile antibodies
  • detection of specific antibodies to EBV
  • detection of nucleic acid of EBV in the blood

Pregunta 27

Pregunta
Raspberry tongue is typical for
Respuesta
  • Scarlet fever
  • Measles
  • Chickenpox

Pregunta 28

Pregunta
The most common neoplasm in HIV infection is
Respuesta
  • Kaposki‘s sarcoma
  • Pulmonary carcinoma
  • Melanoma

Pregunta 29

Pregunta
The aminotransferases (ALT and AST) in acute viral hepatitis are
Respuesta
  • Normal
  • 100 E/L
  • > 1000 E/l

Pregunta 30

Pregunta
Etiological treatment of choice in cholera is
Respuesta
  • penicillin
  • cephalosporin 4-th generation
  • tetracycline

Pregunta 31

Pregunta
Antibiotic of choice for the treatment of Scarlet fever is
Respuesta
  • tetracycline
  • penicillin / beta-lactam
  • gentamicin

Pregunta 32

Pregunta
Meningeal irritation includes
Respuesta
  • nuchal rigidity, hyperesthesia
  • diminished tendon reflexes
  • altered mental status

Pregunta 33

Pregunta
Route of transmission in Lyme disease is
Respuesta
  • via tick bite
  • via drinking unpasteurized milk
  • via mosquito bites

Pregunta 34

Pregunta
The most common causative agent of pneumonia in AIDS patients is
Respuesta
  • Mycoplasma pneumoniae
  • Pneumocystis jiroveci (carinii)
  • Hantavirus

Pregunta 35

Pregunta
Typical clinical manifestation of tetanus is
Respuesta
  • confusion
  • periodic muscle rigidity
  • permanent muscle rigidity and periodic seizures

Pregunta 36

Pregunta
Antibiotic of choice for treatment of Erythema migrans is
Respuesta
  • Cefrtiaxone
  • Doxycycline
  • Gentamycine

Pregunta 37

Pregunta
Measles rash
Respuesta
  • appears after 24 h after the disease onset
  • the disease starts with it
  • appears on 3-5th day of disease onset

Pregunta 38

Pregunta
At risk of acute viral hepatitis C are
Respuesta
  • intravenous drug abusers
  • newborns in poor sanitary conditions
  • travellers to tropical countries

Pregunta 39

Pregunta
The rash of meningococcemia is
Respuesta
  • hemorrhagic necrotic, localized predominantly on the lower limbs and buttocks
  • vesicular, diffuse
  • vesicular, highly pruritic

Pregunta 40

Pregunta
Initial treatment of infectious diarrhea includes
Respuesta
  • rehydration
  • antibiotic
  • correction of ↓K

Pregunta 41

Pregunta
On suspicion of acute viral hepatitis the minimum laboratory TESTS are
Respuesta
  • alkaline phosphate, gamma glutamyl transferase
  • urine (bile pigments), serum (ALT and AST, bilirubin)
  • complete blood count, electrolytes, acid-base metabolism

Pregunta 42

Pregunta
The evolution of Chickenpox rash is
Respuesta
  • macula – papule - vesicle - crust
  • macula- papule - brown pigmentation
  • petechiae- ecchymosis- suffusion

Pregunta 43

Pregunta
The main factor for chronicity in HBV infection is
Respuesta
  • age
  • innate immunity
  • gender

Pregunta 44

Pregunta
The mainstay of diphtheria treatment is
Respuesta
  • antibiotics
  • antitoxin serum
  • corticosteroids

Pregunta 45

Pregunta
Which infection is vaccine-preventable
Respuesta
  • Measles
  • Scarlet fever
  • Lyme borreliosis

Pregunta 46

Pregunta
Koplik spots are pathognomonic sign for
Respuesta
  • Scarlet fever
  • Measles
  • Rubella

Pregunta 47

Pregunta
Jaundice as a clinical manifestation of acute viral hepatitis C is seen
Respuesta
  • in a few patients
  • in the majority of patients
  • in about half of the cases

Pregunta 48

Pregunta
Laboratory minimum for suspected viral hepatitis is
Respuesta
  • urine (bile pigments), serum (ALT and AST, bilirubin)
  • CBC, electrolytes, acid-base balance
  • abdominal ultrasound

Pregunta 49

Pregunta
Meningeal irritation, prolonged clouding consciousness and focal neurological findings are common in
Respuesta
  • meningoencephalitis
  • encephalitis
  • meningitis

Pregunta 50

Pregunta
The incubation period in Shigellosis is
Respuesta
  • 2 weeks
  • 1-7 days
  • 4-6 hours

Pregunta 51

Pregunta
What type of toxin is released by Salmonella bacteria on cell lysis
Respuesta
  • endotoxin
  • neurotoxin
  • enterotoxin

Pregunta 52

Pregunta
Which of the following agents causes hemolytic-uremic syndrome
Respuesta
  • enterohemorrhagic E.coli
  • enteroinvasive E.coli
  • pathogenic E.coli

Pregunta 53

Pregunta
The agent of which disease has teratogenic effect?
Respuesta
  • Rubella
  • Scarlet fever
  • Measles

Pregunta 54

Pregunta
Which of the following statements regarding enteroviruses as causative agents of aseptic meningitis are NOT TRUE?
Respuesta
  • Enteroviruses account for up to 80% of cases of viral meningitis.in children
  • the clinical presentation in children is milder than in adults
  • lymphocytes are predominant in the first 24 hours, later neutrophils prevail

Pregunta 55

Pregunta
Which type of immunity is impaired in HIV infection?
Respuesta
  • humoral
  • cell mediated
  • innate

Pregunta 56

Pregunta
Viral hepatitis A is transmitted via
Respuesta
  • fecal-oral mechanism
  • parenteral mechanism
  • sexual mechanism

Pregunta 57

Pregunta
The most common causative agent of of Infectious mononucleosis is
Respuesta
  • Epstein-Barr virus
  • Cytomegalovirus
  • HIV

Pregunta 58

Pregunta
The main route of transmission of hepatitis C virus is
Respuesta
  • fecal-oral
  • intravenous usage
  • sexual

Pregunta 59

Pregunta
The rash in Scarlet fever is ???
Respuesta
  • maculo-papules, vesicular, fast evolution of stages
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribed

Pregunta 60

Pregunta
The mental status in tetanus is
Respuesta
  • blurred
  • alert
  • hallucinations are typical

Pregunta 61

Pregunta
Typical Measles rash is
Respuesta
  • maculo-papular rash appearing on the first day of the disease
  • maculo-papular rash, confluent, appears on the 4-5 the day
  • discrete maculo-papular rash fades after 3 days

Pregunta 62

Pregunta
Which type of meningitis is characterized by the following CSF findings – lymphocytic pleocytosis, elevated protein and decreased glucose level
Respuesta
  • viral
  • purulent
  • tuberculous

Pregunta 63

Pregunta
Which of the following conditions are NOT AIDS-defining illness?
Respuesta
  • Herpes zoster
  • Kaposki’s sarcoma
  • Esophageal candidiasis

Pregunta 64

Pregunta
Cholera initially presents with
Respuesta
  • chills and high fever
  • diarrhea ” rice water” type
  • intractable vomiting

Pregunta 65

Pregunta
Which of the following microorganisms is associated with diarrhoea after antibiotic therapy or severe operations
Respuesta
  • Cl. difficile
  • Salmonella
  • E.coli

Pregunta 66

Pregunta
Diarrheal syndrome in shigellosis is characterised by
Respuesta
  • large amount of watery stools + abdominal pain
  • sparse, bloody mucoid stools + tenesmi
  • voluminous liquid, ” rice water” type stools

Pregunta 67

Pregunta
A pregnant woman in first trimester had contact with a sick child, suspected to have rubella. How could you manage her
Respuesta
  • to clarify if the child has Rubella
  • to recommend abortion on medical grounds
  • to determine her immunity by serology

Pregunta 68

Pregunta
The most common presentation of Lyme borreliosis is
Respuesta
  • erythema migrans
  • arthritis
  • neuritis

Pregunta 69

Pregunta
The most common initial complaints in acute viral hepatitis are
Respuesta
  • fatigue, anorexia, nausea, loss of appetite
  • severe abdominal pain radiating to the shoulders and vomiting
  • fever and diarrhoea

Pregunta 70

Pregunta
First choice antibiotic for treatment of pertussis is
Respuesta
  • ceftriaxone
  • macrolides
  • amikacin

Pregunta 71

Pregunta
Empirical treatment on suspicion of bacterial meningitis includes
Respuesta
  • 3rd generation Cephalosporins + Vancomycin
  • Penicillin + Metronidazole
  • 3rd generation Cephalosporins + Clindamycin

Pregunta 72

Pregunta
Thick pseudomembrans, spreading across the pharyngeal mucosa and bleeding while dislodging, are characteristic for
Respuesta
  • mononucleosis
  • diphtheria
  • strepto pharyngitis

Pregunta 73

Pregunta
Pustula maligna is typical for
Respuesta
  • Anthrax
  • Mediterranean spotted fever
  • Tularemia

Pregunta 74

Pregunta
Anthrax infection results from
Respuesta
  • exposure to cattle and goats
  • tick bite
  • mosquito bite

Pregunta 75

Pregunta
Acute hepatitis C becomes chronic in
Respuesta
  • 30-80%
  • < 2%
  • >90%

Pregunta 76

Pregunta
The stages in the course of HIV/AIDS infection are
Respuesta
  • early HIV infection, latency period, AIDS
  • catarrhal period , rash period , convalescent period
  • initial intoxication period, period of generalized lymphnodulomegaly, period of hepatosplenomegaly

Pregunta 77

Pregunta
Serological markers of acute viral hepatitis B are
Respuesta
  • HBsAg (+) and anti HBc IgM (+)
  • HBsAg (+) and anti HBc total (+)
  • anti HBsAg (+) and anti HAV IgM (+)

Pregunta 78

Pregunta
Arthralgia in acute viral hepatitis presents with
Respuesta
  • joint pain without swelling and redness
  • swelling, redness and forced position
  • swelling without pain and redness

Pregunta 79

Pregunta
Tache noire (black spot) at the site of the tick bite represents
Respuesta
  • painless ulcer covered with black (necrotic) crust
  • painless oval or round pink or red skin plaque> 5 cm
  • painful hot red plaque with raised edges

Pregunta 80

Pregunta
Which of the following findings IS NOT characteristic of infant meningitis?
Respuesta
  • bulging fontanelle, Lessage sign
  • distended abdomen
  • crie encephalique

Pregunta 81

Pregunta
The screening test for HIV infection is
Respuesta
  • anti HIV (ELISA)
  • viral RNA (PCR)
  • anti HIV (immunoblot)

Pregunta 82

Pregunta
The rash in Mediterranean spotted fever is
Respuesta
  • maculopapular
  • vesicular
  • erythematous

Pregunta 83

Pregunta
Which diseases in not vaccine preventable
Respuesta
  • Lyme borreliosis
  • Poliomyelitis
  • Measles

Pregunta 84

Pregunta
The most common electrolyte abnormalities in patients with diarrhea are
Respuesta
  • hyponatremia and hypokaliemia
  • hypercalcemia and hyperkaliemia
  • hypernatriemia and hyperchloremia

Pregunta 85

Pregunta
Acyclovir is recommended to which of following cases
Respuesta
  • Chicken pox - mandatory
  • Chicken pox in immunocompromised patients
  • Kaposi sarcoma

Pregunta 86

Pregunta
Which of the following statements regarding leptospirosis IS NOT true”
Respuesta
  • Leptospirosis is a biphasic illness with multiorgan involvement
  • Gentamycin is the antibiotic of choice
  • Infection is acquired during walking or bathing in rivers

Pregunta 87

Pregunta
At risk for development of Herpes Zoster are
Respuesta
  • adolescents (aged 11-19 years)
  • patients with HIV infection
  • newborns

Pregunta 88

Pregunta
Characteristic clinical manifestation of enteroviral infections is
Respuesta
  • Herpagina
  • Gingivostomatitis
  • Exudative pharyngitis

Pregunta 89

Pregunta
The rash in Scarlet fever is
Respuesta
  • small maculopapules predominantly in the axilar and inguinal regions
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribe

Pregunta 90

Pregunta
Inflammatory diarrhea is commonly caused by
Respuesta
  • Shigella sp., Campylobacter jejuni, Cl. difficile
  • Viruses, enterotoxigenic E. coli
  • S. aureus, B. cereus, most Salmonella sp.

Pregunta 91

Pregunta
When is ART warranted
Respuesta
  • For all HIV positive regardless of CD4 count
  • CD4<200 cells/µL
  • CD4< 350 cells/µL

Pregunta 92

Pregunta
In the case of infectious mononucleosis-like symptoms, it is important to consider
Respuesta
  • primary HIV infection
  • neoplasms
  • syphilis
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