297549
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace más de 10 años
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Pregunta 1
Pregunta
Which form of Glycogen Phosphorylase is relatively inactive?
Respuesta
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Phosphorylase A
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Phosphorylase B
Pregunta 2
Pregunta
In phosphorylase B, where is the N terminus?
Respuesta
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Floating free in the cytoplasm
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Attached to the protein body
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Unattached from protein
Pregunta 3
Pregunta
Which of the forms of glyocgen phosphorylase is most effected by cellular AMP/ATP levels?
Respuesta
-
Phosphorylase A
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Phosphorylase B
Pregunta 4
Pregunta
Which of the following phosphorylates Glycogen Phosphorylase?
Respuesta
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Phosphorylase B Kinase
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Phosphorylase A Kinase
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Phosphorylase Kinase
Pregunta 5
Pregunta
What protein causes the dephosphorylation of phosphorylase?
Respuesta
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Protein phosphatase
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Protein phosphorylase
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Prokein Kinase P
Pregunta 6
Pregunta
What is needed for the reaction of Phosphorylase B --> A to reverse itself?
Respuesta
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Water (and a lack of inhibiting AMP)
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Water (and a lack of inhibiting ATP)
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Water (and a lack of inhibiting GMP)
Pregunta 7
Pregunta
What is different about Phosphorylase A to B?
Respuesta
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Ser14 has been phosphorylated
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Tyr14 has been phosphorylated
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Thr14 has been phosphorylated
Pregunta 8
Pregunta
What difference does phosphorylating Glycogen phosphorylase make?
Respuesta
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Makes the relaxed form much more likely
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Makes the taut form much more likely
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Deactivates it entirely
Pregunta 9
Pregunta
How does phosphorylase B Kinase connect Glycogen Phosphorylase levels to the level of stimulation?
Respuesta
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It is activated by Ca2+- when the muscle is stimulated, glucose is needed and so glycogen is broken down
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It is deactivated by Ca2+- when the muscle is stimulated, glucose is not needed and so glycogen isn't broken down
Pregunta 10
Pregunta
What part of Phosphorylase B Kinase binds to Calcium?
Respuesta
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Calmodulin
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Calsequestrin
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Troponin C
Pregunta 11
Pregunta
Which parts of phosphorylase B kinase are regulatory?
Respuesta
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Alpha and beta
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Alpha and gamma
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Gamma and beta
Pregunta 12
Pregunta
Which part of phosphorylase B kinase is catalytic?
Respuesta
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Gamma
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Delta
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Beta
Pregunta 13
Pregunta
In phosphorylase B kinase's Ca2+ binding sites, what are the affinities?
Respuesta
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2 high 2 low
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4 high
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4 low
Pregunta 14
Pregunta
What protein causes the phosphorylation of Phosphorylase B Kinase?
Respuesta
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cAMP dependent Protein Kinase
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Adenylate Cyclase
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Glycogen Phosphorylase
Pregunta 15
Pregunta
What is another name of cAMP dependent protein kinase?
Respuesta
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Protein Kinase A
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Protein Kinase B
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Protein Kinase C
Pregunta 16
Pregunta
What is the role of inhibitor one?
Respuesta
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To bind to protein phosphatase, activating it
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To bind to protein phosphatase, inhibiting it
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To bind to protein kinase A, activating it
Pregunta 17
Pregunta
What is contained in the N terminus domain of Glycogen Phosphorylase?
Respuesta
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The catalytic site
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The allosteric effector site
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The regulatory subunit
Pregunta 18
Pregunta
How does glycogen get from it's binding domain to the catalytic site?
Respuesta
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A hydrophobic tunnel
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A hydrophillic tunnel
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A lipophobic tunnel
Pregunta 19
Pregunta
Why is glycogen phosphorylase's site in a deep groove?
Respuesta
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To prevent AMP from entering
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To prevent ATP from entering
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To prevent water from entering
Pregunta 20
Pregunta
What happens if water enters the active site?
Respuesta
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Nothing
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The enzyme is deactivated
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Hydrolysis occurs instead of phosphorolysis
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