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Pain

b.graham Pathophysiology and Pharmacology 1 2015 Inglés 19 fichas

Fichas del conjunto (19)

  1. 1There are two types of pain:sharp
    dull/throbbing
  2. 2Pain receptors are known as _____nociceptors
  3. 3What are the two types of nociceptor fibres?A-delta fibers - mechanical/thermal
    C-fibers - as above but also substances/chemicals released by damaged tissue
  4. 4A-delta fibers are:larger, thinly myelinated fibres -> impulsed travel faster -> acute, sharp
  5. 5C fibers are:smaller, non-myelinated -> slow, burning, aching pain
  6. 61st order neurone:picks up sensation and travels to dorsal spinal cord
  7. 72nd order neurone in the spinal cord can travel along 4 tracts:1. spino-spinal (flexor reflex arcs)
    2. spinothalamus tract
    3. spinoreticular tract
    4. spinomesencephalic tract
  8. 83rd order neurone is located in the ________, from there can travel to the ______________ and ___________thalamus
    somatasensory cortex (discriminatory ascpect)
    and
    limbic areas (cingulate gyrus/insula) (emotional and motivation aspects)
  9. 9What are the 4 types of analgesics?1. Non-steroidal anti-inflammatory drugs (NSAID) e.g. aspirin
    2. Local anaesthetics
    3. Opioids: endorphin, enkephalin, dynorphins
    4. Opioids: antidepressants
  10. 10Local anethetics and anti-inflammatory drugs work _______ while Opioids and Alpha2 agonists work _______ and ________peripherally
    peripherally and centrally
  11. 11You can categorise pain according to what 3 things?1. Origin: e.g. deep somatic pain
    2. Quality e.g. radiating
    3. Severity: e.g. acute or chronic
  12. 12What is Allodynia?pain due to a stimulus which does not normally provoke pain
  13. 13What is hyperalgesia?increased sensitivity to pain
  14. 14Hypoalgesiadiminished pain in response to normally painful stimulus
  15. 15What is paraesthesia?alteration of pain sensations into 'pins and needles' or tingling sensation
  16. 16Noxious stimuli is detected by __________nociceptors
  17. 17Pain information travels in ascending pathways to the somatosensory cortex and associated areas via _____________, _________, _________ and _________ pathwayslateral
    spinothalamic
    spinoreticular
    spinomesencephalic
  18. 18Pain is regulated via descending pathways involving that ____, ________ and ____________ in the dorsal spinal cordPAG
    raphe manus
    substantia gelatinosia
  19. 19Opioid recepts ________ nerve signalsinhibit

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Pathophysiology and Pharmacology 1 2015 Fichas sobre Pain, creado por b.graham el 08/06/2015.
Creado por
b.graham
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