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Lecture 13
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- 1Seratoninin Raphe, seratonin nuclei, go everywhere, long axons, pick up signal from the synapse
- 2what do nuclei have?Lots of Cell bodies
- 3what do nuclei have?lots of cell bodies
- 4What does an agonist drug do?Binds and alot of Na+ flows in
- 5homeostasisequilibrium, alot mor than normal and it tries to bring it down
- 6How is firing stopped?receptors are pulled into the membrane to hide them, the receptor is then chopped off,with only one left, agonist still hits it, but not alot comes in
- 7what is one way tolerance is builtAgonist makinf too much fireing, and then homo. down regulates to only 1 receptor.
voltage changes - 8what does binging lead to?Down regulating
- 9What is desentisitationwhen you tkae an agonoist and it acts on the post syn,doesnt want to stay in this stage
- 10upregulatinggrows more
- 11receptors are made of:pretein (DNA)
- 12Max numbers of recptors boundPlateu
- 13when the plateu goes down:It is desenthysized
- 14Antagonist effectNorms->Agonist Blocks, no excitation, too little activity, ->Upregulates->Back to normal
- 15What else caused own regualtion?When the drug causes spilage on NT in pre syn. terminal. (Ampthtaimine)
- 16What are some Nt?Acetlcholine, norepinipherine, domapine, seratonin
- 17THousands of What make up nucleinucleous
- 18Tolerancecan be due to down regulation, resptors that take away
- 19Synaptic desentisitationAfter down regulation when there are onle a couple or receptors and no more agaonist, then up regulatiod occurs
- 20A drug can block..the uptake, and increase the availability in the synapse
- 21How is a drug spilled in the synapse?Drug blocks vesicle storage at vesicular transporter and spills
- 22what does an antagonist do?blocks activity,postsynaptic membrane senses a decrease in activity and up regulates the number of available receptors
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- college Bio 36 Fichas sobre Lecture 13, creado por maxytrejo1 el 30/10/2013.
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- maxytrejo1
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