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Sugars

Jackson Thompson Human Structure Function Kindergarten Inglés 18 fichas

Sugars

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  1. 1EnantiomersMirror imagesEnantiomers
  2. 2Diastereomershave unique names (glucose, galactose, manose)Diastereomers
  3. 3Anomers(stereoisomers) with asymmetric center at C1Anomers
  4. 4Sugar AlcoholHas OH on Carbon 1Sugar Alcohol
  5. 5Sugar AcidC1 or C6 is oxidizedSugar Acid
  6. 6Amino Sugaramino group substituted for Hydroxyl. ex glucosamine, Sialic acidAmino Sugar
  7. 7Ribose vs. DeoxyriboseRNA vs. DNA, presence of hydroxyl on the 2' carbonRibose vs. Deoxyribose
  8. 8Glycogen vs. AmylopectinGlycogen - soluble, easily dissolved, highly branched (animals)
    amylopectin - insoluble, heating or cooking, long chains fewer branches (plants)
    Glycogen vs. Amylopectin
  9. 9Glycogenglucose storage, α(1->4) linkage, many
    α(1->6) linkages
    Glycogen
  10. 10Amylopectinglucose storage in plants, α(1->4) linkage, some
    α(1->6) linkages
    Amylopectin
  11. 11Cellulosemajor constituent of plant cell walls, beta(1->4) linkages. Every glucose flipped over, forms microfibrilsCellulose
  12. 12O-linked oligosaccharideslink to protein visa glyosidic bond on serine or threonine OH. Play a roll in recognition, interaction, and enzyme regulation. Alternates with phosphorylationO-linked oligosaccharides
  13. 13N-linked oligosaccharidesLinked to protein via Asparagine in specific sequence (Asn-X-Ser/Thr).
    Tend to be complex and branched, secretory.
    N-linked oligosaccharides
  14. 14Glycosaminoglycans (GAGs)Linear polymers of repeating disaccharides. Usually modified, negatively charged. ex. Hyaluronate, HeparinGlycosaminoglycans (GAGs)
  15. 15ProteoglycansProteins that have GAGs covalently linked to serine/ threonine. Synthesized by adding sugars to core protein (in the Golgi). Sometimes found in extracelleular matrix. ex. Versican, SerglycinProteoglycans
  16. 16LectinsGlycoproteins that recognize and bind to specific oligosaccharides. (sugar-binding proteins). A factor in:
    cell-cell recognition, cell adhesion to extracellular matrix, cell interaction with chemokines and GF, disease-causing microorganism recognition, inflammation control
  17. 17C-type lectinscontain C++ to facilitate carbohydrate bonding.C-type lectins
  18. 18Selectinscell-cell recognition in mammalian cell membranes. Similar to C-lectins.Selectins

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Kindergarten Human Structure Function Fichas sobre Sugars, creado por Jackson Thompson el 07/09/2022.
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