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Lipoprotein and Enzyme Function

gina_evans0312 Year 2 Inglés 28 fichas

Fichas del conjunto (28)

  1. 1Cylomicrons- TransportTriacylglycerols, phospholipids and cholesterol
  2. 2Cylomicrons- MovementFrom intestine to periperal cells
  3. 3Cylomicrons- Main ApolipoproteinApoB48
  4. 4Cylomicrons- DestructionCleaved by cells with LPL into Remnant particles
  5. 5Remnant Particles- MovementFrom peripheral cells to liver, where dietary cholesterol is removed
  6. 6VLDLs- TransportEndogenously synthesized TAGs
  7. 7VLDL- MovementFrom liver to periphery
  8. 8VLDL's- Main ApolipoproteinApoB100
  9. 9VLDLs- DestructionBroken down by LPL on peripheral cells into IDLs
  10. 10LDLs- TransportVLDL remnants- rich in cholesterol
  11. 11LDLs- ApolipoproteinB100 (changes conformation to bind to receptors in liver/peripheral tissue)
  12. 12LDLs- Uptake80% by ApoB/E receptors, the rest recirculate
  13. 13LDL to HDL ConversionIn peripheral tissues, excess cholesterol can be converted to HDLs by adding TAGs
  14. 14HDL's- TransportCholesterol
  15. 15HDL's- MovementFrom periphery to liver
  16. 16HDL's- Extra RoleMetabolism of other particles
  17. 17HDL's- Main ApolipoproteinApoAI/AII
  18. 18ApoAI/AII- RolesActivation/Inhibition of LCAT
  19. 19ApoAI/AII StructureRepeat units known as Kringles and a protease domain
  20. 20HTGLHepatic Triglyceride Lipase
  21. 21HTGL- RoleRemoves T.A.G's from passing T.A.G rich particles/ removes LGL digested remnants
  22. 22HTGL- LocationLiver plasma membranes
  23. 23LPLLipoprotein Lipase
  24. 24LPL- RoleDigestion of chylomicrons and VLDL's
  25. 25LPL- LocationVascular endothelial cell membranes
  26. 26MTPMicrosomal Triglyceride Transfer Protein- Assists in binding of TAG to VLDL
  27. 27LCATLecithin Cholesterol Acetyl Transferase
  28. 28LCAT- RoleEsterification of cholesterol in HDLs

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(Lipids) Year 2 Fichas sobre Lipoprotein and Enzyme Function, creado por gina_evans0312 el 24/01/2014.
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gina_evans0312
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