Asthma Treatment (Short Term)

Pregunta	Respuesta
Main Methods of Treatment	Inhalation- gets drugs where needed but limits drugs possible
'Treaters'	Bronchodilators
Beta-2 Agonists	Used to cause bronchodilation
SABA	Short acting beta agonists- act in mins, last 3-5 hours
SABA Example	Salbutamol
LABAs	Long Acting Beta Agonists- delayed onset, last 12 hours
LABAs Example	Salmeterol
Beta Agonist Side Effects	Tremors, palpitations, headache & nervous tension (they can stimulate B1 receptors)
Theophylline- Effect	Non selective phosphodiesterase inhibition, inc in cAMP and bronchodilation
Theophylline- Theraputic range	Narrow
Theophylline- Side Effects	Tremor, nausea, insomnia
Theophylline- Toxicity	Cardiac arrythmias, convulsions
Theophylline- Metabolism	CYP450- so any drugs that inhibit metabolising enzymes will inc theophylline levels
Antimuscarinics- Effect	Block Ach stimulation of smooth muscle
Antimuscarinics- Ipratropium (Effect)	Short acting muscarinic that binds non selectively
Antimuscarinics- Ipratropium (Administration)	Water soluble, little enters circulation
Antimuscarinics- Ipratropium (Timing)	Slow peak of action (30 mins) lasts 3-6 hours
Antimuscarinics- Ipratropium (Side Effects)	Dry mouth, throat irritation, blurred vision

Resumen del Recurso

	Creado por gina_evans0312 hace alrededor de 10 años