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Week 1 - Cell Organization

Mellie Montoya Foundations 1 Inglés 30 fichas

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  1. 1cytoplasmsite of many metabolic pathways and protein synthesis; includes the cytoskeleton; thick solution composed of water, salts, and proteins contained by cell membrane; cytosol + organelles (all material inside the cell and outside of the nucleus)
  2. 2golgi apparatuscarbohydrate modification and maturation of membrane and secretory proteins; modification, sorting, and packaging of proteins and lipids for either secretion or delivery to another organelle
  3. 3endoplasmic reticulumprotein synthesis and glycosylation; synthesis of proteins for distribution to many organelles; calcium storage, drug metabolism, and fatty acid synthesis (synthesis of most lipids)
  4. 4lysosomesintracellular degradation (degradation of cellular components and extracellular particles)
  5. 5plasma membraneinterface of cell to external environment; consists of phospholipid bilayer with embedded proteins; selectively permeable; involved in cell adhesion, signaling, and ion conductivity
  6. 6mitochondriaATP production by oxidative phosphorylation
  7. 7peroxisomesoxidative reactions; oxidation of toxic molecules
  8. 8ribonucleic acid (RNA)polymeric molecule implicated in various biological roles in coding, decoding, regulation, and expression of genes
  9. 9lipidsnaturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins (ex. vit A, D, E, and K), monoglycerides, diglycerides, triglycerides, phospholipids, etc; main biological functions include storing energy, signaling, and acting as structural components of cell membranes
  10. 10gated transportselective pores restrict the movement of large macromolecules but allow diffusion of small molecules (ex. nuclear transport, primary cilium)
  11. 11nucleuscontains main genome; DNA and RNA synthesis
  12. 12endosomessorting of endocytosed material
  13. 13transmembrane transportmembrane bound translocators transport proteins across membranes (ex. ER translocation, mitochondria)
  14. 14vesicular transportmembrane bound vesicles loaded with cargo ferry molecules between compartments (ex. Golgi transport, endocytosis and exocytosis)
  15. 15phagocytosisingestion of large particles and delivery to lysosomes
  16. 16pinocytosisingestion of small bits of the plasma membrane with extracellular fluid
  17. 17receptor-mediated endocytosisendocytotic mechanism in which specific molecules are ingested into the cell. The specificity results from a receptor-ligand interaction. Receptors on the plasma membrane of the target tissue will specifically bind to ligands on the outside of the cell
  18. 18exocytosisdurable, energy-consuming process by which a cell directs the contents of secretory vesicles out of the cell membrane and into the extracellular space
  19. 19cytoskeletonmicrotubules, intermediate filaments, and microfilaments; mechanical support. cell shape, movement; critical for protein, RNA, and organelle anchoring and transport in both the cytoplasm and the nucleus; plays role in mitosis and cytokinesis; form specialized organelles (cilia and flagella)
  20. 20mitosispart of the cell cycle in which chromosomes in a cell nucleus are separated into two identical sets of chromosomes, each in its own nucleus
  21. 21cytokinesisthe physical process of cell division, which divides the cytoplasm of a parental cell into two daughter cells. It occurs concurrently with two types of nuclear division called mitosis and meiosis, which occur in animal cells
  22. 22intermediate filamentsconnects adjacent epithelial cells into sheets; resists shear forces, compression, stretching by controlling the viscoelasticity of cytoplasm; anchors organelles; form non-polar flexible rope-like structures
  23. 23actin microfilamentscontrol cell shape and movement; major component of muscle; flexible and polarized; form microvilli, sarcomeres; nuclear actin involved in transcription, nuclear transport; found in all cells; in motile or muscle cells, arranged in 3D network that cells use to generate force
  24. 24microtubulesmajor component of mitotic spindle; have structural polarity with a + and a - end; organized in cells from the centrosome; minus end always embedded in centrosome; grow and shrink by dynamic instability; main highways in the cell; form cilia and flagella (9+2)
  25. 25centrosomemicrotubule organizing center (MTOC); contains hundreds of gamma-tubulin rings from which microtubules polymerize; contains centrioles (no role in microtubule organization)
  26. 26microtubule associated proteins (MAPs)assist in microtubule dynamics and the movement of cargo along microtubules
  27. 27motor proteinsATP hydrolysis (energy) = large scale structural changes to generate mechanical force; play role in movement of organelles and macromolecular complexes too large to move by diffusion; play role in cell division and cell movement; head domain for motor activity + cargo binding domain
  28. 28kinesinsbelong to large superfamily with related structure and functions; all move on microtubules towards plus end (away from MTOC and towards cell periphery - anterograde movement)
  29. 29dyneinsbelong to small family of motors with similar structure to kinesins but move towards minus end of microtubules (retrograde movement); divided into two groups (1. cytoplasmic, found in call cells 2. axonemal, found in cilia and flagella)
  30. 30myosinlarge superfamily of motor proteins; interact with actin microfilaments or thin filaments of actin (in muscle) to generate force; associated with actin to form contractile structures; in a non-muscle cell, association with actin leads to cell locomotion

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Descripción
Foundations 1 Fichas sobre Week 1 - Cell Organization , creado por Mellie Montoya el 20/08/2015.
Creado por
Mellie Montoya · ago 2015
Actualizado
19 feb 2016
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10
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cell organizationweek 1
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