Nucleic acids

Nucleic acids

1. Nucleotides

   • (deoxy)Ribose +base +phospahte groups
   • Phosphodiester bond
     • between riboses
       • 3' to 5'
     • negative charge

2. Nucleosides

   • (deoxy)Ribose +Base only

3. Bases

   • Purines
     • Adenine +Guanine
     • Two rings (one six sided one 5 sided imadozole)
       • form b-n glycosidic link with ribose at N9
   • Pyrimidine
     • Cytosine + Thymine (DNA) +Urasil (RNA)
     • single 6 sided ring
       • form b-N glycosidic link with ribose at N1
   • faces of base rings hydrophobic
     • N atoms hydrophilic
     • stacking

4. nucleosides can be phosphorylated to form nucleotids