Test
Pharm exam #3
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Preguntas del test (96)
1Which of the following is not safe during pregnancy?
- AACEI
- BARB
- CAliskiren
- DNone are safe during pregnancy
2Which of the following metabolic changes is not seen with use of loop diuretics?
- ADecrease in Ca
- BDecrease in K
- CIncrease in Mg
- DIncrease in Glucose
3Which of the following is not a side effect of thiazides?
- AHyponatremia
- BMetabolic alkalosis
- CHypouricemia
- DSexual dysfunction
4Which of the following G IIb/IIIa receptor antagonists has a long half life and is irreversible?
- AASA
- BTirofiban
- CAbciximab
- DEptifibatide
5Which of the following is not a side effect of osmostic diuretics?
- AElectrolyte imbalance
- BAnuria
- CLocal pain and venous irritation
- DAcute renal failure
6Which of the following is a characteristic of LMWH?
- ALow bioavailability
- BMonitored with PTT
- CInexpensive
- DRenally excreted
7Which of the following is not a side effect of Aliskiren?
- ADecrease in uric acid
- BDiarrhea
- CAbdominal pain
- DAngioedema
8Which of the following is not correct regarding eplerenone?
- AIt is more expensive than spironolactone
- BLess endocrine-related side effects than spironolactone
- CLower chance of hyperkalemia
- DHigher affinity for aldosterone receptors
9Which of the following is not a side effect of ACEI?
- ACough
- BHypotension
- CGynecomastia
- DHyperkalemia
10Acetazolamide causes metabolic alkalosis because you excrete bicarbonate, and therefore it is best to administer this diuretic to metabolic acidic patients.
- AVerdadero
- BFalso
11Which of the following are better to avoid with use of potassium-sparing diuretics?
- AACEI
- BLithium
- CEplerenone
- DAmiloride
12Choose which of the following you would administer to a CKD patient
- AThiazide
- BCCB
- CACEI
- DARB
13Which of the following diuretics act on the distal convoluted tubule to block sodium reabsorption?
- AAldosterone antagonists
- BThiazides
- CLoop diuretics
- DCAIs
14You always have drug interactions with NSAIDS with use of diurectics because they inhibit prostaglandins which antagonizes the action of diurectics
- AVerdadero
- BFalso
15Which diuretic would you not want to use in a patient who has gout?
- ALoop diuretics
- BSodium channel blockers
- CAldosterone receptor antagonists
- DThiazides
16How does Conivaptan promote free water diuresis?
- ABy stimulating cGMP resulting in vascular smooth muscle relaxation
- BBy being excreted unchanged and causing water to be retained within the proximal tubule and descending loop of Henle due to the freely permeable water
- CBy blocking the epithelial sodium channels on principal cells and cause sodium excretion
- DBy antagonizing vasopressing
17Lisinopril antagonizes the AT1 receptor
- AVerdadero
- BFalso
18Which of the following metabolic changes would you see with the use of a thiazide?
- AIncrease Mg
- BIncrease Ca
- CDecrease glucose
- DIncrease in potassium
19Hydrochlorthiazide is used more than chlorthalidone because it is more potent and research has shown that it produces a greater reduction in systolic blood pressure.
- AVerdadero
- BFalso
20In which of the following conditions would not benefit from the use of vasopressin receptor antagonists?
- AUrinary frequency
- BCHF
- Ccirrhosis
- DSIADH
21Which of the following is a side effect Bosentan?
- AEpistaxis
- BVisual disturbances
- CLiver cirrhosis
- DDyspepsia
22Which of the following would require careful dosing in a renal failure patient?
- AFondaparinux
- BAbciximab
- CWarfarin
- DArgatraban
23Which of the following drug combinations would not be beneficial?
- AMetolazone and Bumetanide
- BHCTZ and ARB
- CACEI and ARBs
- DFurosemide and Lisinopril
24Liver toxicity is a side effect of tolvaptan?
- AVerdadero
- BFalso
25Which of the following have short half-lives
- AUFH
- BWarfarin
- CASA
- DFondaparinux
- EVorapaxar
- FAbciximab
- GEptifibatide
- HTirofiban
26Why do we need to overlap warfarin and heparin or LMWH in a patient with a new VTE?
- ABecause you want to deactivate antithrombin
- BIt takes about 5 days to replace activated clotting factors with dysfunctional clotting factors
- CIt takes about 5 days to replace Protein C and Protein S
- DYou should never overlap warfarin with LMWH or UFH
27Which of the following antiplatelets can cause dyspnea?
- APrasugrel
- BTicagrelor
- CClopidogrel
- DTiclopidine
28Which of the following prostanoids can cause epistaxis?
- AEpoprosternol
- BIloprost
- CTreprostinil (Remodulin)
- DTreprostinil (Tyvaso)
29Which of the following is safe during lactation?
- ADabigatran
- BDirect X inhibitors
- CWarfarin
- DIndirect X inhibitors
30Which of the following antiplatelets can be used when a patient has had a cardiac event while taking clopidogrel?
- ATiclopidine
- BTicagrelor
- CPrasugrel
- DUFH
31Which of the following antiplatelets is used with aspirin in post-ACS patients?
- ATicagrelor
- BTiclopidine
- CPrasugrel
- DClopidogrel
32Liver toxicity is a side effect of conivaptan
- AVerdadero
- BFalso
33Which of the following antiplatelets is hardly used in clinical practice and can cause neutropenia?
- ATicagrelor
- BClopidogrel
- CPrasugrel
- DTiclopidine
34Which of the following antiplatelets is contraindicated for patients with a history of stroke/TIA?
- APrasugrel
- BTicagrelor
- CClopidogrel
- DTiclopidine
35Ranolazine can be used ONLY in acute angina attacks
- AVerdadero
- BFalso
36It is important to hold indirect factor X inhibitors for at least 48 hours
- AVerdadero
- BFalso
37Why is it important to place a patient who develops HIT on another anticoagulant?
- ATo decrease the platelet count.
- BTo prevent a prothrombotic condition
- CTo prevent bleeding.
- DTo induce a prothrombotic condition
38Which of the following is not part of the treatment for HIT?
- AStop heparin products
- BStop warfarin until platelet count is above 150,000
- CUse alternative anticoagulants
- DGive a high dose of warfarin when restarting
39Which of the following drugs can cause serious cardiovascular and thromboemolic events if dose and hemoglobin range is not taken into account?
- ACalcitriol
- BERAs
- CESAs
- DDopamine
40Which of the following is not a characteristic of argatraban?
- AMonitored by PTT
- BHepatic elimination
- CDecrease in INR
- DCan be used for treatment of HIT
41Which of the following is absolutely not safe during pregnancy?
- AWarfarin
- BHeparin/LMWH
- CFondaparinux
- DIV DTIs
42Which of the following is correct regarding warfarin?
- AIt causes less GI bleeding than dabigatran
- BIt causes more GI bleed than Rivaroxaban
- CIt causes less GI bleeds than Apixaban
- DIt causes less ICH in Direct Factor X inhibitors and Dabigatran
43How long should one hold warfarin before major surgery
- A24 hours
- B48 hours
- C6 hours
- D5 days
44Which of the following has no reversal agent or is irreversible?
- ALMHW
- BUFH
- CWarfarin
- DRivaroxaban
45Which of the following is not a side effect of Acetazolamide?
- AMetabolic acidosis
- BKidney stones
- CParesthesia
- DHypernatremia
46Which of the following is NOT a cause for concern of sodium nitroprusside-induce cyanide toxicity?
- ARenal dysfunction
- BIncreasing dose during therapy
- CPost-MI
- DIncreasing duration of therapy
47Which of the following is true about SELECTIVE beta blockers? Choose all that apply:
- ASafe to use in COPD patients
- BHas a slightly better metabolic effect
- CLoses selectivity at lower doses
- DHas little effect in patients with reversible airway disease
48Which of the following is a correct rationale as to why we would use a beta blocker to treat MI/angina peri-operatively? Choose all that apply:
- ATo decrease production of aqueous humor
- BTo decrease HR
- CTo decrease contractility
- DTo decrease portal hypertension
- ETo inhibit vasodilatation or arteriolar spasms over the cortex
- FTo decrease oxygen demand
49Which of the following is not a characteristic of fondaparinux?
- AIt directly affects factor X
- BIt is renally excreted
- CIt has a long half-life, so not good for bridging with warfarin
- DThere is still risk of HIT
50The benefit to using calcitriol over vitamin D analogs is that it can decrease the chance of hypercalcemia and hyperphosphetemia.
- AVerdadero
- BFalso
51Which of the following are nonselective beta blockers? Choose all that apply:
- AAtenolol
- BCarvedilol
- CPropranolol
- DMetoprolol
- ENadolol
- FTimolol
- GLabetalol
- HSatelol
52Which of the following diuretics is the most potent?
- AThiazides
- BPotassium-sparing diuretics
- CLoop diuretics
- DSodium channel blockers
53Which of the following is correct regarding warfarin reversal agents?
- APCC are more efficient than FFP
- BPCC is usually given in a large volume
- CFFP and PCC are given with Vitamin K
- DFFP has larger risk of thrombosis
54Which of the following is a side effect of hydralazine ONLY?
- ASodium and water retention
- BHypertrichosis
- CPrecipitation of angina
- DInduced MI
55Which of the following would you never want to give with nitrates due to their drug interaction?
- AProstanoids
- BERAs
- CHydralazine
- DPDE-5 drugs
56Which of the following prostanoids can cause sepsis?
- AEpoprostenol
- BTreprostinil (Remodulin)
- CIloprost
- DTrerostinil (Tyvaso)
57Which of the following prostanoids can cause severe hypotension?
- AEpoprostenol
- BTreprostinil (Remodulin)
- CTreprostinil (Tyvaso)
- DIlioprost
58Treprostinil (Tyvaso) is an inhaled prostenoid
- AVerdadero
- BFalso
59Which of the following are NOT safe to use during pregnancy? Choose all that apply:
- APDE-5 drugs
- BSodium nitroprusside
- CERAs
- DProstenoids
- ERiociguat
60Which of the following antiplatelets works by inhibiting ADP receptor?
- AGP IIb/IIIA inhibitors
- BVorapaxar
- CP2Y12 inhibitors
- DASA
61Why are endothelin receptor antagonists used as a cardiac drug?
- AIt's ability to block ETB receptor
- BBecause of its vasoconstricting effects
- CBecause of its ability to release NO to cause vasodilation
- DIt's ability to block ETA receptor
62Which of the following causes an increase in INR?
- ADabigatran
- BHypothyroidism
- CBactrim with use of warfarin
- DShort gut syndrome
63Nitrate tolerance can be fixed by having a nitrate-free period lasting from 4-8 hours
- AVerdadero
- BFalso
64How do calcium-channel blockers cause decrease in contractility, SA node rate, and AV node conduction velocity?
- ABy blocking sodium influx, causing calcium overload through the sodium/calcium exchanger
- BBlocking calcium channels, blocking calcium influx, causing dilation in arterial smooth muscle leading to decrease in afterload
- CBlocking calcium channels, blocking calcium influx, causing dilation in venous smooth muscle leading to decrease in afterload
- DBlocking calcium channels, blocking calcium influx, causing dilation in venous smooth muscle leading to decrease in preload
65When using dihydropyridines, one must be careful when using it with digoxin and beta blockers, as this may cause additive negative effects on cardiac conduction
- AVerdadero
- BFalso
66Which of the following is correct regarding nitrates and their mechanism of action?
- AThey cause arterial dilation
- BThey are denitrated to NO, increasing cGMP and causing increase in dilation
- CThey are denitrated to NO, decreasing cGMP and causing increase in dilation
- DReleases NO from the drug itself, causing vasodilation
67Which of the following is a reason for loss of response to ESA therapy?
- AHypertension
- BBenign process
- CIron deficiency
- DPure white cell aplasia
68Which of the following adrenergic agonists can cause a decrease in renal blood flow as an adverse effect?
- AEpinephrine and Norepinephrine
- BDobutamine and Epinephrine
- CNorepinephrine and Dopamine
- DPhenylephrine and Dobutamine
69Which of the following adrenergic agonists can cause reflex bradycardia?
- ADobutamine
- BEpinephrine
- CPhenylephrine
- DDopamine
70Which of the following is NOT a side effect of alpha-1 adrenergic blockers?
- AFloppy Iris Syndrome
- BProlonged QT interval
- CBradycardia
- DOrthostatic hypertension
71ARBs are not used as first line therapy despite the less occurrence of side effects.
- AVerdadero
- BFalso
72Which of the following is not a side effect of potassium-sparing diuretics?
- AGI symptoms
- BOtotoxicity
- CMetabolic acidosis
- DHyperkalemia
73Which of the following IV iron products can alter magnetic resonance imaging studies?
- AIron dextran
- BFerric gluconate
- CFerumoxytol
- DFerric carboxymaltose
74Which of the following IV iron products can cause an anaphylactic reaction?
- AIron dextran
- BFerric gluconate
- CFerumoxytol
- DFerric carboxymaltose
75Iron sucrose is given in divided doses, about 10 dialysis sessions
- AVerdadero
- BFalso
76Which of the following is not a side effect of loop diuretics?
- AHypomagnesemia
- BHypocalcemia
- CHypernatremia
- DOtotoxicity
77Which of following phosphate binders can cause metabolic acidosis?
- ACalcium carbonate
- BCalcium acetate
- CRenagel
- DRenvela
78Aliskiren inhibits the conversion of angiotensin I to angiotensin II.
- AVerdadero
- BFalso
79Ranolazine inhibits myocardial cell sodium/calcium exchanger, preventing ischemia-induced contractile dysfunction and delaying the onset of angina
- AVerdadero
- BFalso
80Which of the following a Class I drug?
- APropafenone
- BPropranolol
- CAmiodarone
- DDiltiazem
81Dronedarone is a
- Abeta-blocker
- Bpotassium channel blocker
- Csodium channel blocker
- Dcalcium channel blocker
82Lidocaine is
- Afor atrial arrhythmias
- Bthe strongest among the sodium channel blockers
- Cused as a local anesthetic
- Da class IC drug
83Which is the best drug for use in patients with CHF or structural heart disease?
- AFlecainide
- BPropafenone
- CAmiodarone
- DVerapamil
- EDofetilide
84Choose all that would be used for cardioversion of atrial fibrillation.
- ADofetilide
- BIbutilide
- CVerapamil
- DProcainamide
- ELidocaine
- FDigoxin
85Which of the following is a side effects of Amiodarone?
- APulmonary fibrosis
- BIncrease in iodine
- CPhotosensitivity
- DThese are all side effects of Amiodarone
86Which of the following has beta-blocking activity?
- APropafenone
- BFlecainide
- CIbutilide
- DProcainamide
87Which of the following does NOT rely on renal function for elimination
- ASotalol
- BDofetilide
- CDigoxin
- DAmiodarone
88How does adenosine function in stress testing?
- ACauses vasodilation in healthy arteries, revealing the diseased coronary arteries
- BCauses vasoconstriction in healthy arteries, revealing the diseased coronary arteries
- CCauses vasodilation in diseased arteries, revealing the healthy coronary arteries
- DCauses vasoconstriction in diseased arteries, revealing healthy coronary arteries
89Which of the following is correct regarding digoxin?
- AInhibits potassium channels, decreasing intracellular potassium
- BInhibits sodium-potassium ATPase, increasing sodium concentration thereby increasing calcium concentration
- CCauses negative inotropic effects
- DCauses positive dromotropic/chronotropic effects
90Choose which of the following is true for Amiodarone
- AShorter half life than dronedarone
- BSlightly more effective than dronedarone in Afib patients
- CHigh risk of side effects
- DMore GI side effects
- EI2 in structure and effects thyroid
- FDoes not have negative inotropic effects
- GCannot be used for CHF
91How do calcium channel blockers work as antiarrhythmics?
- AThey dilate arterial smooth muscle
- BMostly effects the sodium channels in atrial and ventricular tissues and Purkinjie fibers
- CActs on the SA and AV node
- DBlocks sodium channels
92Which of the following is correct regarding the use of beta blockers perioperatively?
- AShould be continued in patients who are already on a beta blocker
- BUse of them perioperatively in any situation is standard of practice
- CPerioperative beta blockage started within one day or less before noncardiac surgery decreases risk of stroke, death, hypotension, and bradycardia
- DIt is not a clinical contreversy
93Which of the following drugs should you be cautious due to chance of developing QT prolongation?
- ADronedarone
- BBeta-blockers
- CFelcainide
- DDigoxin
94Which of the following drug classes could cause Torsades de Pointes?
- ABeta blockers
- BClass IA drugs
- CClass IB drugs
- DCalcium channel blockers
95Which of the following drugs can be used for ventricular arrhythmias?
- APropafenone
- BDigoxin
- CDofetilide
- DIbutilide
96Which of the following CANNOT be used for cardioversion?
- ADofetilide
- BIbutilide
- CPropafenone
- DVerapamil
Información
- Descripción
- Made up questions for exam 3
- Autor
- Diana Flores
- Idioma
- English
- Visitas
- 125
- Etiquetas
- Valoración
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