Test
HAEMATOLOGY_2011
Preguntas del test (9)
1In a patient with Budd Chiari syndrome, the most common
underlying myeloproliferative disorder is:- AA .CML
- BB. Chronic myelomonocytic leukaemia
- CC. Myelofibrosis
- DD. Essential Thrombocythaemia
- EE. Polycythaemia vera
2What is the most likely cause of a haemolytic reaction due to ABO incompatibility?
- AA. Undetected antigens in the donor blood
- BB. Hospital laboratory error
- CC. Failure to identify the correct patient on sample collection
- DD. Failure to identify the correct patient on transfusion
- EE. Undetected antibodies in the recipient blood
3Which of the following is the most common cause of acquired protein C resistance?
Pregnancy- AB. Malignancy
- BC. Factor V Leiden
- CD. Protein C deficiency
- DE. Factor VIII inhibitor
4What is the most common genetic inheritance pattern of Von Willebrand ’ s disease?
- AA. Autosomal recessive
- BB. Autosomal dominant
- CC. X-linked recessive
- DD. X-linked dominant
- EE. Mitochondrial
5A 74 year old man presents with bruising of his trunk and
lower limbs. Clinical examination reveals
hepatosplenomegaly. His spleen is palpable 5 cm below the costal margin. FBC: Hb 122 WCC 10
Plt 47 His liver function tests are normal as is his coagulate on profile.
His blood film (shown below) demonstrates thrombocytopaenia, poikilocytes and tear drop
cells.
The likely cause of his clinical picture is:- AA. Chronic myelocytic leukaemia
- BB. Myelofibrosis
- CC. Myelodysplasia
- DD. Thalassaemia
- EE. Polycythaemia vera
6A previously well, 33yo woman, with no significant past medical history, presented with petechiae of
the lower limbs with otherwise normal examination. Results of bloods shown:
Hb 130 WCC 7 Plt 15
Blood film reveals decreased platelets only. A diagnosis of idiopathic thrombocytopenia (ITP) is made.
What is the most appropriate initial treatment?- AA Intravenous immunoglobulin
- BB. Prednisone 1 mg/kg daily
- CC. Plasmapheresis
- DD. Romiplostin
- EE. Platelet transfusion
7A 52 yr old man with a history of coeliac disease presents with weight loss, fevers and abdominal bloating. His Hb is 100, WCC 2.4, PLT 100. A CT scan of his abdomen shows intraabdominal lymphadenopathy. Peripheral blood shows circulating atypical lymphocytes. A diagnosis of lymphoma
is suspected. What would be the next best investigation to confirm the diagnosis?- AA. Bone marrow aspirate and trephine
- BB. FNA of an intra-abdominal lymph node
- CC. Excisional biopsy of an intra-abdominal lymph node
- DD. Flow cytometry on peripheral blood
- EE.PET scan
8A 70-year-old man presents with a smoking history of 68-
pack-years. His haemoglobin is 220 (130
–
180) and haematocrit is 0.69 (0.35
–
0.45). EPO level is 4 (4-22). After excluding secondary cau
ses of
polycythemia, what investigation is helpful to confirm
polycythemia rubra vera?- AA. Bone marrow biopsy
- BB. Janus kinase 2
- CC. Philadelphia chromosome
- DD. Fe studies
- EE. Spontaneous erythoid colonies
9A 35 year old female admitted for repair of a fractured neck of femur. Transfused 2 units post-operatively or blood loss. Develops cellulitis managed with flucloxacillin. Discharged uneventfully. 10 days later she represents with lethargy and SOB. Not jaundiced. Hb 70. Blood film shows polychromasia and chistocytes.
What is the most likely cause of her anaemia?- AA. Delayed haemolytic transfusion reaction
- occurs up to day 24 hours up to day 14 - BB. Flucloxacillin induced anaemia
- but schistocytes are usually found in DIC, hemolytic reactions - CC. Sepsis
- DD. Iron deficiency
- EE. Post-operative blood loss
- AA. Delayed haemolytic transfusion reaction
Información
- Descripción
- RACP Haematology Test sobre HAEMATOLOGY_2011, creado por Jeku Jacob el 11/01/2017.
- Autor
- Jeku Jacob
- Idioma
- English
- Visitas
- 5
- Etiquetas
- Valoración
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