Anaemia

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35.1
Averil Tam
Flashcards by Averil Tam, updated more than 1 year ago
Averil Tam
Created by Averil Tam about 6 years ago
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TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. A. Children under three years of age are not predisposed to iron deficiency anaemia. False. Iron deficiency anaemia is common between 6 months and three years of age as this is a period of rapid growth, also many infants and toddlers are inclined to have large quantities of cows milk (which is low in iron) as opposed to other nutrients that are a better source of iron. Cows milk specially if consumed under a year of age can also lead to gastrointestinal blood loss due to cow’s milk protein intolerance.
TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. B. The child is on a nutritionally adequate diet. False. Children over a year of age should not consume more than 600 mls of milk a day in order to achieve a balanced diet.
TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. C. Breast milk is a poor source of iron as compared to cow’s milk. False. Breast milk is a better source of iron than cow’s milk as the iron in breast milk has better bioavailability.
TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. D. It is important to check haemoglobin and do iron studies in this child. True. This particular child is at risk of iron deficiency anaemia given his age and the fact that he consumes large quantities of cows milk in his diet.
TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. E. Children have a lower mean corpuscular volume (MCV) as compared to adults. True. After three months of age children have a lower MCV as compared to adults and reach adult values around puberty. Age specific ranges should therefore be referred to when interpreting test results. Generally an MCV less than 70 femtolitres is considered abnormal in children. In the first three months of life red blood cells are normally macrocytic and an MCV less than 100 femtolitres is considered low and suggests the need to investigate for causes such as thalassemia.
TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. F. Blood loss can lead to iron deficiency. True. Chronic or severe acute blood loss can lead to iron deficiency. Therefore keep this possibility in mind even in cases of iron deficiency anaemia.
TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. G. A low serum ferritin level is diagnostic of iron deficiency and a normal level rules out the same. False. A low serum ferritin level (<10 microgs/L) is diagnostic of iron deficiency however a normal level does not rule out iron deficiency as ferritin is a non-specific marker of inflammation and can be elevated in any inflammatory state including intercurrent infections which are common in childhood.
TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. H. Treatment of iron deficiency anaemia consists only of elemental iron given in a dose of 6mg/kg body weight daily for three months. False. Treatment of iron deficiency anaemia consists of elemental iron given in a dose of 6 mg/kg body weight daily for three months. It’s important to also address dietary deficiencies. Milk intake should not exceed about 400ml a day in toddlers and cows milk should not be the principal milk source in infants under a year of age.
TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. I. Follow up in a child on treatment for iron deficiency does not need repeat haemoglobin levels prior to 3 months. False. Follow up for iron deficiency includes repeating haemoglobin levels and doing a reticulocyte count at one to two weeks after commencing the child on iron. Response to therapy is a confirmation of the diagnosis as well.
TRUE/FALSE? 1. 18 month old boy, unusually pale, otherwise healthy (wt and ht 90th %ile). On a solid diet but prefers his bottle, consuming 1.5L of milk a day. J. Children can tolerate very low haemoglobin levels without cardiovascular compromise. True. Children with no underlying cardiovascular or pulmonary disorders can tolerate very low haemoglobin levels without cardiovascular compromise.
TRUE/FALSE? 2A. Iron supplementation is an adjunct to treatment in thalassemia. False. Iron supplementation is contraindicated in thalassemia as it will worsen the iron overload.
TRUE/FALSE? 2B. Macrocytic anaemia in an exclusively breast fed infant is most likely due to gut malabsorption of vitamin B12. False. Macrocytic anaemia secondary to vitamin B12 deficiency in exclusively breast fed babies is mostly due to maternal vitamin B12 deficiency.
TRUE/FALSE? 2C. Females do not get Glucose 6 phosphate dehydrogenase (G6PD) deficiency. False. G6PD deficiency is an X linked recessive condition. However, females may be G6PD deficient by virtue of being homozygous for the X linked mutation or as a result of the phenomenon of lyonisation with inactivation of the normal allele.
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