Flashcards
Bacterial Cell Wall
Cards in this deck (41)
- 1structure present in Archaea instead of peptidoglycanpseudomurein
- 2another term for peptidoglycanMurein
- 32 fxns of peptidoglycanmaintenance of the cell integrity, resistance from osmotic lysis
- 42 sugar backbones of peptidoglycanNAG (N-accetyl glucosamine) &
NAM (N-acetylmuramic acid) - 5tetra amino side chainsL-alanine, D-glutamic acid , DAP (Diaminophenelic acid) in G(-) or L-lysine in G(+), D-alanine
- 6bonds that connect the peptidoglycan monomers- Glyosidic bonds
- 7process which create the cross bridging between peptidesTranspeptidation
- 8Usable form of aaL-form
- 9advantage for having D-form aaprotection against digestion of proteases (not easily detected)
- 10peptide cross link in G-DAP - D-ala
- 11peptide cross link in G+L-lys to D-ala
- 12characteristic of G- cell walldense
- 13characteristic f G+cell wallthick peptidoglycan layer
- 14cause of thick peptidoglycan layerpeptide interbridge (made up of 5 glycine)
- 15Starting material in peptidoglycan synthesisfructose-6-phosphate
- 16To which molecule does NAG interact with to form NAM?Uridine Diphosphate
- 17How is NAG converted to NAM?Lactyl group is added to C-3 of UDP-NAG to form UDP-NAM
- 18T or F: tRNA & ribosomes are used in peptide addition in peptidoglycan synthesisFalse (NOT used)
- 19transport lipid which carries NAG-NAM-5AAundecaprenyl-monophosphate
- 202 processes occurring in the cell wall upon peptidoglycan synthesisTransglycosylation & Transpeptidation
- 21examples of beta-lactam antibioticspenicillin, cephalosporins
- 22mechanism of beta-lactam antibioticsthe absence of the peptide bridge due to the binding with transpeptidase enzyme
- 23example of Glycopeptide antibioticsvancomycin
- 24mechanism of glycopeptide antibioticsprevents the formation of peptide cross-links by bindingto the penta-peptide side chains
- 25mechanism of bacitracinPrevents the dephosphorylation of bactoprenol resulting to the inhibition of monomer transport
- 263 types of peptidoglycan hydrolases1. Glycan-strand hydrolyzing enzyme,
2. Endopeptidase hydrolyzing enzyme,
3. N-acetylmuramoyl-L-amanine amidase enzyme - 27mechanism of Glycan-strand hydrolyzing enzyme- Hydrolyzes the B-1,4 glycosidic bonds bet NAM& NAG
- 28mechanism of Endopeptidase hydrolyzing enzymeBreaks the cross link between the peptides
- 29mechanism of N-acetylmuramoyl-L-amanine amidase enzymebreaks the connection bet. the sugar backbone & aa side chain
- 30describe: G+ cell wall- Thick peptidoglycan
- Thin periplasmic space - 31unique structures in G+ cell wallsteichoic acids & lipoteichoic acids
- 32fxn of teichoic acidsvirulence factor required for host colonization
- 33Teichoic acids which extend until the cell membranelipoteichoic acids
- 34fxn of Lipoteichoic acidsstructural support
- 35components of Lipoteichoic acidsglycerol or ribitol
- 36Most abundant protein in OMBraun’s lipoprotein
- 373 parts of lipopolysaccharideLipid A, core polysaccharide, O side chain
- 38fxn of O side chainbacteria become less susceptible to detection of antibodies
- 39special structures in outer membraneporins
- 404 reagents in Gram stainingCrystal violet, iodine, ethanol, safranin
- 41differential sep in G stainingethanol decolorization
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- Biology 123: Microbial Physiology Flashcards on Bacterial Cell Wall , created by Nicole Bolo on 09/09/2014.
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- Nicole Bolo · Sep 2014
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- Feb 19, 2016
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