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NEUR3018 - L9.

Zsofi Dombi NEUR3018 English 24 cards

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  1. 1Hippocampus locationlocated under the cerebral cortex, in the medial temproal lobe
  2. 2Memory definitionfaculty of the mind by which information is encoded, stored and retrieved
  3. 3Why is memory important? (Eysenck, 2012)vital to experiences, without remembering past events we could not learn / develop language, relationships, personal identitiy
  4. 4Amnesia definitionthe profound loss of memories, in the presence of relatively preserved cognitive abilities
  5. 5Types of amnesia1. psychogenic: results from psychological factors
    2. organic: results from damage to the brain through physical injury
  6. 6Anterograde amnesia definitionthe inability to form new memories
  7. 7Retrograde amnesiaThe lost of pre-exisitng memories to conscious recollection beyond an ordinary degree of forgetfulness
  8. 8Hippocampal amnesiadamage to the medial temproal lobe
  9. 9Patient HM- had bilateral medial temproal lobectomy to treat his epilepsy
    - reduction in epilepsy but heavy anterograde amnesia and temporally graded retrograde amnesia
  10. 10What is preserved in hippocampal patients?- short term memory: tested by digit span
    - procedural memory: tested by mirror drawing
    - general cognitive memory: tested by the Wisconsin Crad Sorting Test
  11. 11The taxonomy of Memory- long term memory: explicit and implicit memory
    - explicit memory: semantic and episodic memory
    - implicit memory: priming, classical conditioning, procedural skills, non-associative learning
  12. 12Explicit memory in the brainmedial temporal lobe
  13. 13Implicit memory in the brain- non-associative learning: reflexes
    - classical conditioning: emotional - amygdala, skeletal - cerebellum
    - priming: neocortex
    - procedural skills - striatum
  14. 14the standard consolidation theory- by Squire and Alvarez (1995)
    -the hippocampus is believed to rapidly integrate and bind together information transmitted from distributed cortical networks that support the various features of a whole experience in order to form a coherent memory trace
    -as memories mature, the role of the hippocampus would gradually diminish, leaving extrahippocampal regions, presumably cortical areas, to become independently capable of sustaining memories and mediate retrieval
  15. 15problem with the standard consolidation theory- individuals growing up with hippocampal damage have normal semantic knowledge, only impairment in episodic memory
    - patient FRF had reserved semantic memory, but severe retrograde autobiographical amnesia
  16. 16revised taxonomysemantic memory: independent of hippocampus
  17. 17Squire & Bayley (2007)graded retrograde amnesia is regularly reported in hippocamapl patients
  18. 18Cipolotti et al (2001)patient V.C.
    had amensia for very remote memories
  19. 19Steinvorth et al (2005)assessed remote autobiographical memories in HM and WR
    - semantic memories without hippocampus are not rich in detail
  20. 20The Multiple Trace Theory- proposed by Nadel and Moscovitch (1997)
    - every remembering: a new trace
    - older memories: become semanticised
    - the hippocampus retains a permanent role in memory storage and retrieval as long as memories exist
  21. 21Gilboa et al (2004)- fMRI study using family photographs
    - hippocampal activation is related to the vividness rather than the age of memory
    - support the multiple trace theory
  22. 22O'Keefe & Nadel (1978)proposed that hippocampus stores cognitive maps
  23. 23Martin et al (2005)- hippocampus play a long-lasting role in spatial memory
    - examined retrograde memory in rats (partial / complete)
  24. 24Maguire et al (2006)- patient TT: taxi driver in London
    - remembered and navugated good in major roads
    - impaired navigation when minor roads used

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NEUR3018 Flashcards on NEUR3018 - L9., created by Zsofi Dombi on 12/04/2018.
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