Flashcards
Learning 2
Cards in this deck (15)
- 1Major input to the purkinje cells?•Parallel fibers
•Climbing fibers - 2Major input to granule cells?Mossy fibers
- 3Why do purkinje cells have lots of dendrites?Receive loads of info from granule cells
- 4Hippocampus important for:Spatial memory + word recall
- 5Long term potentiation (LTP)•Releasing a big stimulus
•AP is higher/Lower in response
•Sustained response - 6The 3 major afferent pathways:•Dendate region
•CA3
CA1 - 7What are these 3 pathways known together asTrisynaptic circuit of hippocampus
- 8Electrophysiological recordings:•EC recording
•IC recording
•In vivo recording - 9Receptors important for learning + memory?AMPAR + NMDAR (post synaptic receptors)
- 10Induction of LTP First stage1) Low levels of stimulation release glutamate, binds to AMPAR receptors=NA+ influx
- 11Second stageNMDAR receptors can’t open, Mg2+ ion blocking their pores
- 12Third stageLTP induction releases shit ton of glutamate, opens shit ton of AMPAR receptors= shit ton of Na+ influx
- 13Fourth stageDepolarisation of cell occurs, AMPAR receptors open as depolarisation is enough to remove Mg2+ ion
- 14Fifth stageNa+ and Ca2+ influx thru AMPAR receptors
- 15Sixth stage^Ca2+ enables long term change in responsiveness
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- Organisms & environment Flashcards on Learning 2, created by Taher Miah on 05/05/2018.
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- Taher Miah
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