Ch 28: Drugs for Angina Pectoris and Myocardial Infarction

Olivia McRitchie
Flashcards by Olivia McRitchie, updated more than 1 year ago More Less
Olivia McRitchie
Created by Olivia McRitchie over 1 year ago


NCLEX Pharmacology Flashcards on Ch 28: Drugs for Angina Pectoris and Myocardial Infarction, created by Olivia McRitchie on 08/21/2018.

Resource summary

Question Answer
Isosorbide dinitrate (Dilatrate SR, Isordil) Organic nitrate
Isosorbide mononitrate (Imdur, Ismo, Monoket) Organic nitrate
Nitroglycerin (Nitrostat, Nitro-Dur, Nitro-Bid) Organic nitrate
Atenolol (Tenormin) Beta-adrenergic blocker
Metoprolol (Lopressor, Toprol XL) Beta-adrenergic blocker
Nadolol (Corgard) Beta-adrenergic blocker
Propranolol (Inderal, Innopran XL, Inderal LA) Beta-adrenergic blocker
Timolol (Betimol) Beta-adrenergic blocker
Amlodipine (Norvasc) Calcium channel blocker
Diltiazem (Cardizem, Cartia XT, Dilacor XR) Calcium channel blocker
Nicardipine (Cardene) Calcium channel blocker
Nifedipine (Adalat CC, Procardia XL,) Calcium channel blocker
Verapamil (Calan, Covera-HS) Calcium channel blocker
Ranolazine (Ranexa) Anti-anginal (miscellaneous drug)
What 2 categories can antianginal medications be placed into? Drugs that terminate an acute angina episode in progress, and those that decrease the frequency of anginal episodes
How do antianginal drugs accomplish the goals of either terminating an acute anginal episode or decreasing the frequency of the episodes? Reducing myocardial demand for oxygen by slowing heart rate, dilating the veins, causing the heart to contract with less force, or lowering BP
How does ranolazine work? It shifts the metabolism of cardiac muscle cells so that they use glucose as the primary energy source rather than fatty acids.
What is the primary therapeutic action of the organic nitrates? Their ability to relax both arterial and venous smooth muscle, which reduces the amount of blood returning to the heart (preload).
What is a common and potentially serious problem with long-acting organic nitrates? Tolerance
Transdermal patches of nitrates should be removed for how many hours a day? 6 to 12 hours
Oral doses of nitrates should be dosed to cover how many hours a day? 12 to 18 hours
Beta-blockers are the drugs of choice for the prophylaxis of what kind of angina? Stable angina
Beta-blockers may make what kind of angina worse? Vasospastic (Prinzmetal's) angina
What is the most important action that calcium channel blockers have for patients with angina? They relax arteriolar smooth muscle.
Calcium channel blockers are preferred for what kind of angina? Vasospastic aangina.
When giving sublingual nitrates, you should take BP before administration and how long after administration? 5 minutes
What side effects should the patient be assessed for after being given nitrates? Excessive hypotension, dysrhythmias, reflex tachycardia, headache that does not subside in 15-20 minutes (or when accompanied by neurologic changes), or decreased urinary output.
Outside of BP, what other information should the nurse collect before and after giving nitrates? Location and characteristic of pain
What OTC drug should patients consult with their healthcare about? Aspirin
Where should patients place nitrate transdermal patches? Hair free areas of the torso
What parts of the physical assessment should a nurse emphasize when assessing a patient on a nitrate? Neurologic, cardiac, and respiratory
Aside from aspirin, what other drugs should a patient not take while on nitrate therapy? Drugs for erectile dysfunction.
If a patient has anginal chest pain that doesn't subside after taking a nitrate tablet, what should the patient do? Do not take additional nitroglycerin tablets and call 911
Thrombolytics are most effective when delivered how long after the onset of myocardial infarction symptoms? 20 minutes to 12 hours
Thrombolytics are largely ineffective if given how long after myocardial infarction symptoms? 24 hours
Unless contraindicated, 160 to 325 mg of what drug is given as soon as myocardial infarction is suspected? Aspirin
Clopidogrel (Plavix) Adenosine diphosphate-receptor blocker
Prasugrel (Effient) Adenosine diphosphate-receptor blocker
Ticagrelor (Brilinta) Adenosine diphosphate-receptor blocker
Eptifibatide (Integrilin) Glycoprotein IIb/IIIa
Abcixamab (ReoPro) Glycoprotein IIb/IIIa
Tirofiban (Aggrestat) Glycoprotein IIb/IIIa
Upon diagnosis of myocardial infarction in the ER, the patient is placed on what for 48 hours (or until PCI is completed)? Heparin
Patients with persistent pain, heart failure, or severe hypertension may receive what drug in IV form for 24 hours following the onset of pain? Nitroglycerin
Beta blockers can reduce myocardial infarction-associated mortality if they are administered within how many hours of MI onset? 8 hours
What 2 angiotensin-converting enzyme (ACE) inhibitors can be given 2 patients experiencing myocardial infarction? Captopril (Capoten) or lisinopril (Prinivil, Zestoretic)
Drug therapy with ACE inhibitors is most effective when started within how many hours after the onset of symptoms? 24 hours
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