Flashcards

Pathogenic fungi

Jumael Zafar BIOL 122: Impact of microbes English 14 cards

Cards in this deck (14)

1The three medically important myco's- Mycoses
- Allergies
- Mycotoxins
21. True pathogens- Infect healthy host
- Grown in high temps and low o2
- Possess thermal dimorphism.
3More features- Most are asymptomatic in host
- Has glomus (important micorrhizal fungi
- Not parasitic
4E.g. histoplasmosis- The most common true pathogen.
- Only common to certain regions
5E.g. coccidioides imitis- Most common in alkaline soil of west USA.
- at 37 degrees, sporangia forms.
62. Opportunistic pathogens- Requires an immunocompromised host.
- Global
- Shows no adaptations to host environment
7More features- Poor prognosis
- Benign to chronic systemic infections
- Many species
8E.g. Candida albicans- Causes thrush
- Dimorphic, hyphal form is aggressive.
- 4th biggest killer in tertiary hospitals but most common fungal killer
9E.g. aspergillosis- 8 cause disease
- A.fumigatus is a thermophile
- Colonises lung
10Dermatophytes- Keratin lovers
- Ringworm and athlete's foot
- Superficial infections
11Fungal drugsAzoles e.g. Ketoconazole, fluconazole
Polyenes e.g. Nystatin, amphotericin B
-All are ergosterol dependent
5-fluorocytosine inhibts RNa synthesis
12Phytopathogens- Mature, umcompromised (m)
- immature non compromised (i)
13M (Specific)necrotrophic - kill nost celll evoking resistance e.g. honey fungus cause root rot
biotrophic - nutrients from living host cases wheat rust e.g. Puccinia graminis
14I- Broad host range
- Soil-borne attack roots
- e.g. Phytothphora infestans
Irish potato famine (1845)

Description: BIOL 122: Impact of microbes Flashcards on Pathogenic fungi, created by Jumael Zafar on 08/12/2018.
Created by: Jumael Zafar
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