Flashcards
Untitled
Cards in this deck (9)
- 1hydrophilic aarginine
aspartic acid
glutamic acid
serine
threonine
cystein
aspargine
glutamine
histidine - 2pi cation interractionarginine
tryptophan
histidine
phenylalanine
lysine
tyrosine - 3myoglobin153 ac
8 alpha helix and hydrophobic core - 4small heat shock proteins(shsps)1)mol size 12-43 kda
2)bind proteins in non-native conformations and prevent them from aggregation
3)under stress they are induced to an active state
4)are involved in many basic cellular processe
5)accumulate in cells of patients with alzheumer and parkinson with high amount of aggregated protein
6)mutations have been related to cataract,myopathy,neurophaty
Assemble to longer aggregated complexes that are activated under stress
Monomeric chaperones Hsp40,hsp70.hsp100 help to disassemble - 5heat shock proteinschaperones
1)small heat shock proteins-shsps
2)chaperones-monomeric proteins
3)chaperonons-large,hollow oligomeric structures - 6soft cationscu2+
cd2+
pt2+
Hg2+ - 7most important cations in hyman bodyna+
mg2+
k+
ca2+ - 8zn binding sitea)cys-cys-cys-cys
b)his-cys-cys-cys
c)asp-his-his-his - 9non-pathological amyloidscurlin
chaplins
hydrophobin eas
proteins of the chorion of the egg shell
spidroin
intermetal domain of pmell 7
ure2p(prion)
sup35p(prion)
rnq1p(prion)
het-s(prion)
neurospecific isoform of cpeb(prion)
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- Flashcards on Untitled, created by alenasunflower on 15/11/2014.
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- alenasunflower
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