Flashcards
CSIM1.49
Cards in this deck (10)
- 1What local factors effect wound healing?Mechanical factors
Edema
Ischemia and necrosis
Foreign bodies
Low oxygen tension - 2What systemic factors effect wound healing?Inadequate perfusion
Inflammation
Diabetes
Nutrients
Metabolic diseases
Immunosuppression
Connective tissue disorders
Smoking - 3Describe the systemic effects of inflammation and their underlying mechanismsHigh levels of Acute-phase proteins
Increased Leukocyte numbers
Systemic inflammation and overeating - 4What can an increase in acute-phase protein in systemic inflammation lead to?Amyloidosis and Fever,
Increased blood pressure,
Decreased sweating,
Malaise,
Loss of appetite,
Somnolence, - 5What are the effects of leukocyte numbers is systemic inflammationLeukocytosis (high lekocyte numer) and leukopenia (low lekocyte number)
- 6How is systemic inflammation linked to obesity?In inflamtion high amounts of interleukins are seen, this is also oberserved in the obese
- 7What are the causative agents in chronic inflammtion?Persistent acute inflammation due to non-degradable pathogens, viral infection, persistent foreign bodies, or autoimmune reactions
- 8What are the major cells involved in chronic inflammation?Mononuclear cells (monocytes, macrophages, lymphocytes, plasma cells), fibroblasts
- 9What is a granloma?an inflammation found in many diseases. It is a collection of immune cells known as histiocytes.[1] Granulomas form when the immune system attempts to wall off substances that it perceives as foreign but is unable to eliminate
- 10What is fibrosis?the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process.[1] This can be a reactive, benign, or pathological state. In response to injury this is called scarring and if fibrosis arises from a single cell line this is called a fibroma
Information
- Description
- Flashcards on CSIM1.49, created by v.scudamore on 07/05/2015.
- Created by
- v.scudamore
- Views
- 0
- Rating