Flashcards
Colon histology
Cards in this deck (13)
- 1Mucosa-Smooth without folds
-No villi
-Crypts of Lieberkuhn
-0.5mm straight and extend from lumen to the muscularis mucosae - 2Mucosa-Epithelial lining of columnar cells with abundance of globlet cells and small number of endocrine cells
- 3Epithelium-Turnover of the colonic surface epithelium takes 3 to 8 days
- 4Absorptive cells-Columnar cells
-Basally located round nuclei
-Short microvilli on surface - 5Goblet cells-More in colon than small bowel
-Most abundant in sigmoid and rectum
-1 per 4 columnar cells
-Nuclei compressed basally
-Mucin stains with Alcian blue at pH2.5 and 1.0 - 6Endocrine cells-Colon has less than any other part of GIT
-Located in proximal and distal colon
-Most prominent in base of crypts
-Clear or eosinophilic cytoplasm - 7Paneth cells-Present scattered in caecum and prox A colon
-Absent from rest of colon - 8Lamina propria-Separates the crypts
-Consist of loose, reticular connective tissue - 9Lamina propria-Contains:
Fibroblasts
Capillaries
Macrophages
Plasma cells
Lymphocytes
Scattered mast cells - 10Lamina propria-Solitary lymphoid follicles are present which can displace crypts and extend into the submucosa
-Increase towards the rectum
-Larger in children - 11Submucosa-Contains collagen, reticulin fibres, elastic tissue, nerves, blood vessels, lympahtics, ganglion cells and variable amounts of fat
- 12Muscularis propria-Bands of smooth muscle separated by connective tissue (elastic and collagen)
-Myenteric (Auerbach) plexus is found between both layers - 13Serosa-Located outside of the longitudinal muscle
-Contains blood vessels and lymphatics
-Covered by peritoneum
-Elastic lamina present below the peritoneal cells
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- Frcpath Histopathology (Colon) Flashcards on Colon histology, created by Iain Sheriffs on 12/02/2021.
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- Iain Sheriffs
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