325815
Description
Flashcards by maxytrejo1, updated more than 1 year ago
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Created by maxytrejo1
over 10 years ago
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| Question | Answer |
| Enhancement | motor stimulation, low fatigue low drowsiness higher alert |
| Low doses | high locomoation, high exploration |
| High does | low locomotion, higher sterotypy |
| How does amphetamine disrupts DA synapses | Amph. mimics DA, DA transporters take amphet. to cell, amph, gets inside vesicle and froce DA out, Da in Synpase, forces trsporter to act reverse |
| What does amphetamine influences? | presynaptic cell by causing a lot of DA to be released |
| How amph. dirupts DA synapse | 3Da in Synpase, forces trsporter to act reverse 4.Da builds up in the cleft and bind to recpetors 5. over stimulatio |
| nicotine withdrwal | irritabilty, hunger, decreases HR, sleep disturbances |
| low levels= | desensitization |
| long term= | high nACHR |
| Psycostimulents | influnce cognative and affective functioning behaviors |
| Dopmaine | critical for the expression of motor stimulent effects of psycostimulents |
| Nicotine and Caffine | minor psycostimulents |
| CAffine | non selective antagonist of adenosine recepotrs |
| Nicotine | acts as a nicotinic ACh agonist |
| Psycostimulent dose response fintion is | interted u shape |
| Forebrain DA systms are critical | for the expression of the motor stimulent effects of Major psycostiumulents |
| How do pyscostimulents drirupt DA synapses | Meth fools the cell into dumping lots od dopamine into synapse, causing a surge of exhilaration |
| Apomorphine | rotate away form DA Depletion |
| Amphetamine | Rotate toward DA depleition |
| Most of the effects of caffine is related to: | the abilty to acts as a non selective antagonist of adenosine receptors |
| Negative effects of cafine | anxiety/addiction, increased vasci/blood preasuer, reduced control of fine motor ,movements, stimulation of urnition |
| positive effcts of csffine | increased attention,alterness, lower risk of cardiovasucular disease, low diabetes,increased metabolic rate |
| Tolerance develops | to many effects of caffine |
| Nicotine acts as | ACh agonist |
| What triggers the release of adrenaline into the blood system? | nAChRs found in the adrenal gland |
| What does nicotine exposure increases? | Firing of midbrain DA cells |
| What are withdrawl symptoms might be mediateed by? | Changes in nAChRs |
| 1/2 smokers will die prematurley | caner, carido disease, emphysmea, bronchits, dec. birth weight |
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