372524
Description
Flashcards by maxytrejo1, updated more than 1 year ago
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Created by maxytrejo1
over 10 years ago
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| Question | Answer |
| Schiz. affects | 1%, 2-3% have symptoms |
| Schiz. symptoms develp: | slowley over months and years, many or few symptoms |
| character isitics of people with schiz. | cant keep friends/jobs, anxiety, depression and sucidal thoughts/behaviors |
| first symptoms | irritable/tense/cant concentrate or sleep, |
| 1.Paranoid Schiz. | anxiety, anger, arguing,false belief/harm themselvs or loved ones |
| 2. Disorganized Schiz | child like behavior, problems thinking and explaining ideas, show little emotion |
| 3.Catatonic schiz | grimacing/odd facial expression, lack of activity, rigid muscues/posture, so response to people |
| 4. Undifferentiated Schiz | symptoms of more than one schiz |
| Positive Symptoms | thought disorder, halucinations, delusions: easiest to treat |
| 1. Delusions of Persecution | PS: false beliefs that people are plotting and consipiring against you |
| 2. Delsuions of Grandeur | PS: falsebelifs in your own power and importance. godlike power and special knowledge no one processes |
| 3. Delusions of Control | PS: related to delusions of persecution in a person belives they are being controlled, under a radar or radio planted in their head |
| Shciz have early problems with | anxiety, depression and suicde |
| 4. Halucinations | voices/auditory hallucinations, comment on what they r doing, or insulting, or teing them what to do |
| Negative Symptoms | 1.flattened emotional response, 2. poverty of speech, 3.lack of initiave, 4. persistence, 5.inabilty to express pleasure, 6.social withdrawl |
| Paranoid Disorginized, Catanomic all play into | dopamine |
| What symptoms are most easiest to treat? | positive symptoms |
| Effects on the Frontal Cortex | decreased blood flow, shrunken |
| Ventricles | enlarged, less cortical matter |
| What is simlar to schiz | Bipolar and Maniac |
| Up until when was there no effective treatment : | mid 1950s, insulin shock therapy was used |
| Chlorpromazine | 1950s a drug desighned to work as an antihistmaine found to be effective fro treating schiz: reduces hallucinations, delusions, active, logical thoughts calmed(PS) |
| Haloperidol | 1960s even more effective than Chloropromazine |
| What do both Chloropromazine and Haloperido (Antipsycotics) ? | Block post synaptic DA receptors |
| Dopamin recpetors are? | Metobotropic: G coupled |
| Cocain blocks the | Reuptake of 5ht, Ne, Da- more NT in synapse |
| Cocaine | Causes psychosis becuase of DA |
| Anti psycotoc drugs are? | antagonists, block recpetors on the post synaptic |
| Auto receptor | on the pre synaptic, also blcoked by the agonist: it reguled how much NT is released,how much it sends back to the pre synaptic |
| Anti psycotics block: | Block DA, on the pre(auto) and post, to take out all the synapses |
| In some sense what is the cause of Schiz: | "Da or DA receptors" Drugs that block dopamine receptors treat schiz: |
| Do schiz. have higher circulating levels of DA? | NO |
| Schiz. have more_ | D2 receptors and more extracellular DA than non Schizs |
| cocaine blocks Receptors meaning | it floods the synapse with dopamine which means that high levels of cocaine cause: psycosis |
| Further problems with Schiz | thinking, emotions and behavior: bizarre hallucination, isolation, no emotion, no attention, delusional, loose association |
| Types of Schiz: | 1. Catatonic 2. Paranoid 3. Disorganized 4. Undifferntiated |
| DA path | Sud.Nigra to Striatum VTA to NAcc. to PReferontal |
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