3462271
Description
Flashcards by mollzer1952, updated more than 1 year ago
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Created by mollzer1952
over 8 years ago
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| Question | Answer |
| First line of defense= Innate Immunity | Innate resistance/barriers (ex: skin, mucosa) |
| Second line of defense= Innate Immunity | Initiated by damage to first line of defense, local and systemic inflammation Protects from further injury, prevents infection and promotes healing |
| Third line of defense= Acquired Immunity (Ch. 8) | Adaptive or specific Immunity, slow to develop, has memory cells, rapidly targets and eradicates during second exposure |
| First line of defense: In detail | Physical Barriers: Skin, mucosa of GI tract and respiratory tract; Mechanical Barriers: mucosal cells are routinely replaced to remove bacteria, cleansing by vomit and urination, cilia move mucus to be expelled by coughing |
| (Contd.) First line of defense: In detail | Biochemical Barriers: epithelial derived (ex: mucus, perspiration, saliva, tears, earwax) Antimicrobial peptides toxic to bacterial, fungus and viruses Antimicrobials penetrate/disrupt bacteria cell membranes, are also released by inflammatory cells |
| Second line of defense= Inflammatory response | Initiated by cellular injury and tissue damage Interdependent systems: (1) Mast cell degranulation (release of mediators and chemotactic factors) (2) Activation of plasma protein systems (complement, clotting and kinin systems) (3) Release of mediators from damaged cells |
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