Flashcards
10. Neuromodulation, memory and behaviour.
Cards in this deck (10)
- 1Name the pacemaker neuron of abdominal ganglion in AplasiyaR15
- 2CPGs vs PacemakersCPGs oscillate via reciprocal inhibition
pacemaker integral oscillatory
bursting in pacemaker via intracellular cAMP and Ca and negative feedback - 3list the three modifications of the gill withdrawal reflexes in learning- habituation
- sensitization
- classical conditioning - 4Gill withdrawal reflex in aplysiaGill withdrawal when siphon touched
- plasticity of gill withdrawal reflex compares to leech shortening
- sensitization when shock tail and touch siphon - 5Gill withdrawal reflex habituation and neuromodulatorsrepeated stimuli reduction response
reduction of exocytosis of neurotransmitter release from LE sensory to L7 motor
primary NT is Glutamate
In leech NT is 5-HT - 6sensitisation in gill withdrawal reflexapply excessive stimulation
increase glutamate exocytosis
heterosynaptic facilitation
neuromodulation by 5-HT like in leech - 7short term sensitisationIon channel modulation
decrease s type k+ channel
increase Ca influx
delayed k rectifier
direct effect on sensory machinery - 8long term sensitisationGenetic expression
include MAPK cAMP CREB-1 other ca dependent processes
- new synaptic connection
- prevent memory suppressor genes
long term indirect effect - 9is the molecular mechanism of sensitization universal in invertebrates?yes
- 10How does the mechanisms of sensitization and habituation in in Aplysia compare with those in leeches?in Aplasiya
Gill withdrawal reflex - Gill withdrawal occurs when siphon is touched
reduced response due to repeated stimulation in both
reduction in exocytosis of NT from LE to sensory L7 motor
primary NT is glutamate
sensitisation by excessive stimulation
in leeches shortening reflex
main NT is 5-HT
habituation due to depletion of 5-HT T6-L2
sensitisation due to excitation of of L2 via S overcomes depletion of T6-L2 to excite L2
5-HT neuromodulatory in both
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- Undergrad Animal Behaviour Physiology Flashcards on 10. Neuromodulation, memory and behaviour. , created by Fouz Hussain on 23/05/2022.
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- Fouz Hussain
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