Glycogenolysis

Description

University Biochemistry Flashcards on Glycogenolysis, created by Sophie Mae Neash on 29/11/2013.
Sophie Mae Neash
Flashcards by Sophie Mae Neash, updated more than 1 year ago
Sophie Mae Neash
Created by Sophie Mae Neash over 10 years ago
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Resource summary

Question Answer
What hormones stimulate glycogenolysis? Glucagon and adrenaline
What is the secondary messenger for this process? Cyclic AMP (cAMP)
How is cAMP produced? From ATP using adenyl cyclase
What does cAMP do? Activates Protein Kinase A (PKA)
What does PKA then do? Activates phosphorylase kinase by phosphorylating it.
What does activated PK then do? Phosphorylates (activates) glycogen phosphorylase
What reaction does glycogen phosphorylase catalyse? Glucose-6-phosphate to glucose
Why can glucose not be formed from glycogen in the muscle? As they lack glycogen phosphorylase enzyme
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