40174599
Description
Flashcards by Ginger Scally, updated more than 1 year ago
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Created by Ginger Scally
over 1 year ago
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| Question | Answer |
| Where does glycolysis occur? | In the cytoplasm. |
| What are the net products of glycolysis per glucose molecule? | 2 ATP, 2 NADH, and 2 pyruvate. |
| What is the mnemonic for glycolysis enzymes? | "Hungry Pirates Pick All The Greatest Pizzas Prepared Ever so Perfectly." (Hexokinase, Phosphoglucose Isomerase, Phosphofructokinase-1, Aldolase, Triose Phosphate Isomerase, G3P Dehydrogenase, Phosphoglycerate Kinase, Phosphoglycerate Mutase, Enolase, Pyruvate Kinase.) |
| At which steps is ATP consumed in glycolysis? | Step 1 (Hexokinase) and Step 3 (PFK-1). |
| At which steps is ATP generated in glycolysis? | Step 7 (Phosphoglycerate Kinase) and Step 10 (Pyruvate Kinase). |
| When is NADH produced in glycolysis? | Step 6 (G3P Dehydrogenase). |
| What is the rate-limiting enzyme of glycolysis? | Phosphofructokinase-1 (PFK-1). |
| What activates and inhibits PFK-1? | Activated by AMP and F2,6BP; Inhibited by ATP and Citrate. |
| What are the three key regulatory enzymes in glycolysis? | Hexokinase (Step 1), PFK-1 (Step 3), Pyruvate Kinase (Step 10). |
| What happens to pyruvate under aerobic conditions? | It is converted to Acetyl-CoA via Pyruvate Dehydrogenase and enters the Krebs cycle. |
| What happens to pyruvate under anaerobic conditions? | It is converted to lactate via Lactate Dehydrogenase to regenerate NAD⁺. |
| What is the only pathway that can generate ATP without oxygen? | Glycolysis (Anaerobic glycolysis). |
| Which type of phosphorylation occurs in glycolysis? | Substrate-level phosphorylation (Steps 7 and 10). |
| How is NADH regenerated for glycolysis to continue? | By oxidative phosphorylation (aerobic) or lactate fermentation (anaerobic). |
| What is the mnemonic for glycolysis regulation? | "ATP and Citrate Stop; AMP and F2,6BP Go!" (ATP and Citrate inhibit, AMP and Fructose-2,6-Bisphosphate activate PFK-1.) |
| How much ATP is generated in glycolysis? | 4 ATP total, 2 ATP net. |
| How much NADH is generated in glycolysis? | 2 NADH per glucose molecule. |
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