Flashcards
Exam 2: The Integumentary System

Cards in this deck (62)
- 1Integument- larges organ system of the body
- the "Gatekeeper"
- VASCULAR and innervated
-made up of two parts:
1. epidermis and dermis (the skin)
2. accessory structures (nails, hair follicles, etc.) - 2Functions of the skin1. Protection
2. Prevents (water/fluid loss)
3. Immune function (langerhans cell)
4. Maintains temp
5. Secretion
6. Metabolic regulation (synthesizes melanin and vitamin D)
7. Sensory Perception - 3—(picture)

- 4Danger Sensors =mechanoreceptors
- 5Epidermisstratified, squamous epithelium with keratin
- 6Epidermis: MechanoreceptorsMeissner's Corpuscles
Pacinian Corpuscle
Naked Nerve endings
Nerve Fibers associated with hair
- # per area = sensitivity to touch - 7Meissner's Corpusclesfine touch
at the surface of the skin
- 8Pacinian Corpusclevibration and pressure

- 9Naked Nerve Endingssense pain, hot and cold
- 10Sensory Endings =processes from the dorsal root ganglion neurons
- 11Epidermal Ridgesfingerprints

- 12Dermal Papillae- tiny mounds
- inc area of basal lamina
- strengthens attachment of epidermis to dermis
- causes the overlying epidermal ridges
- 13MelanocytesContains the pigment melanin
- located in the Stratum Germinativum
- 14—(picture)

- 15KeratinocytesALL SKIN CELLS are called this
- 16Thin Skin- covers most of the body
- 3 layers of keratinocytes (thick as a plastic sandwich bag)
- Thin Stratum Corneum - 17—star = acellular

- 18Thick Skin- covers palms of the hands and souls of the feet
- has three layers of keratinocytes
- more keratin - 19—star = acellular

- 205 Layers of the Epidermis

- 211. Stratum CorneumTop layer
(acellular. not cells, but what cells make over time)
- the "horn layer"
- up to 30 layers of keratin
- water resistant
- takes 7-10 days for cells to move from the stratum germinativum to here
- 222. Stratum Lucidum(Acellular. not cells, but what cells make over time)
*** ONLY IN THICK SKIN
- the "clear layer"
- covers stratum granulosum. filled with organelles and keratin
- 233. Stratum Granulosum- the "grainy layer" produce protein fibers
- stops dividing but continues to produce:
Keratin and Keratohyalin
- cells degenerate and die containing tightly interlocked layers of keratin and keratohyalin
- 24Keratina tough fiberous protein
- makes up hair and nails - 25Keratohyalindense granules cross link keratin fibers
- 264. Stratum Spinosum- the "spiny layer"
- contains Dendric (langerhans) cells
- several layers of keratinocytes bound by desmosomes
- cells shrink during fixation but desmosomes remain attached (spiny)
- division continues. thickness of epithelium increases
- 27Dendric Langerhans cellsactive in immune response
- 285. Stratum Germinativumthe Last layer (deepest)
- the "germinative layer"
- has germinative (stem) cells or BASIL CELLS attacked to basil lamina by hemidesmosomes
- **strong bond between epidermis and dermis
- 29Psoriasisimmune system attacks keratinocytes and causes overgrowth/production of cells
- 30Keratinizationthe formation of a layer of dead, protective layers of keratin = acellular
- occurs on all exposed surfaces except the eyes
- skin life cycle 7-10 days - 31Melanin 2 Types: Eumelaninbrown/black hair
- grey black yellow brown
areola
skin - 32Melanin 2 Types: Pheomelaninpink to red
red hair, lips, nipples, glans, penis, vagina - 33Melanocytes function(all have the same amount, but skin color depends on activity)
- in Stratum Germinativum
- protects skin from sun and UV radiation (DNA mutations and burns that can lead to cancer and wrinkles) - 34The two types of melanin produce melanocytes, which are stored in transport vessels called:melanosomes
- 35Carotene- orange yellow pigment
- in orange vegetables and not made by animals
- converted to vitamin A - 36Melanosomesconvert tyrosine to melanin, a pigment
- pigment migrates out of the cell and towards the cells to protect and wraps around them - 37Keratinocyte Uptakesupranuclear
- protects from UV rays - 38Increase in melanosomes caused byexposure to sunlight
- 39Increased number of melanocytesexcessive sun exposure
- 40The Dermisconnective tissue and accessory structures
- between epidermis and dermis
- anchors accessory structures: hair follicles, etc
- 2 components:
1. outer papillary layer
2. deep reticular layer - 41—(picture)

- 42Outer Papillary Layerloose, areolar connective tissue
- small capillaries, lymphocytes, and sensory receptors
- forms dermal papillae between epidermal ridges - 43Deep Reticular Layer- Dense irregular connective tissue
- large blood vessels, lymph vessels, and nerve fibers
- collagen fibers and bundles of elastic fibers - 44Dermal strength and elasticity caused by:1. Collagen fibers: very strong, bend easily
2. Elastic Fibers: strength and can recoil to original shape - 45Skin Damage caused by:damaged collagen fibers
- Wrinkles: due to dehydration, age, hormonal changes, and UV exposure
- Stretch Marks: thickened tissue from weight gain and pregnancy - 46The Dermis: Lines of Cleavagecollagen and elastic fibers arranged in parallel bundles to resist force in a specific direction
- need to cut with these lines to heel properly - 47The Hypodermics (Subcutaneous Layer)- lies below the epidermis and dermis (connected to the reticular layer by connected tissue)
- deposits of subcutaneous fat, and the site of SUBCUTANEOUS INJECTIONS
- stabilizes the skin
- allows separate movement
- made of areolar and adipose tissue
- - 48Accessory (Adnexal) Structures of the Skin- Hair, hair follicles, sebaceous glands, sweat glands, and nails.
- derived from the Embryonic Epidermis (grow down connective tissue and differentiate)
- in the DERMIS
- project through skin surface - 49Functions of the hairHair is keratinized cells
- protection and warmth
- sensitive to very light touch - 50Arrector Pili- pulls up hair
- involuntary smooth muscle
- goose bumps
- sympathetic NS - 51Sebaceous Glands- short duct
- lubricate the hair
- control of bacteria
- exocrine gland - 52—(picture)

- 53Exocrine glands of the skinSebaceous and sweat glands
- 54Sebaceous Glands- some associated with hair follicles
- HOLOCRINE glands (whole cell secreted)
- secrete sebum - 55Sweat Glands (2)CONTROLLED BY SYMPATHETIC NS
- Merocrine (eccrine) sweat gland: watery, electrolyte secretions. palms and souls. flushes out chemicals
- Apocrine sweat gland: in the "A" regions: armpits, nipples and groin. odiferous due to bacterial degradation of secretions
thermoregulation, autonomic ns - 56—picture

- 57—(picture)

- 58—(picture)

- 59Myoepithelial cellscontractile proteins in cytoplasm
- squeezes material out of duct - 60Cell Repairmakes matrix and repairs
- makes new epithelium with granulation tissue - 61—picture

- 62—picture

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- * Sophomore (2 Semester) (ANPS) Flashcards on Exam 2: The Integumentary System, created by Tessia D on 18/03/2016.
- Created by
- Tessia D · Mar 2016
- Updated
- Apr 6, 2018
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