5199303
| Question | Answer |
| What are the two types of neural communication? | Electrical (within neurons) Chemical (between) |
| Name 3 characteristics of a neurotransmitter | -Exists in pre-synaptic axon terminals -Pre-synaptic cells contain enzymes for synthesizing substance -Substance released when AP reaches terminals -Specific receptors recognize the substance -Application of the substance produces changes in postsynaptic potential -Blocking release of the substance prevents nerve impulses |
| is Glutamate inhibitory or excitatory? | Excitatory |
| Name some ionotropic glutamatergic receptors | AMPA, NMDA, Kainate |
| Name and describe the two types of receptors | Left: Ligand-gated receptors (ionotrpic) FAST Direct channel Right: Metabotropic receptors SLOW Indirect control |
| GABA exists in 3 classes, are these excitatory or inhibitory? | Inhibitory |
| Describe these three classes | A – ionotropic, producing fast, inhibitory effects via Cl- channel B – metabotropic, slow inhibitory effects C – like A is ionotropic with a chloride channel |
| Name 2 drugs that influence GABA | Alcohol and Valium |
| Name the pathway of the brain: Acetylcholine | Cholinergic (nuclues basalis) |
| Name the pathway of the brain: Dopamine | Mesostriatial (Mesostriatial and meso limbo-cortical) |
| What is Dopamine used for and what drugs effect it? | Motor control and reward learning (e.g. parkinsons) + Cocaine and MDMA |
| Name the pathway of the brain: Noradrenaline | Locus Coeruleus 4 subtypes of receptors (All metabotropic) |
| Name the pathway of the brain: Serotonin and what does it do? | Raphe Nuclei + Antidepressant (effects: sleep, mood, sexual behaviour and anxiety) |
| Name some ways in which drugs effect pre synaptic mechanisms | |
| Name some ways in which drugs effect post synaptic mechanisms | |
| Name the difference between an agonist and a receptor agonist | |
| Name the difference between a competitive antagonist and non-competitive antagonist |
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