Streptococcus Pyogenes

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Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 about 7 years ago
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Description

Medical Microbiology (Skin Infections) Flashcards on Streptococcus Pyogenes, created by gina_evans0312 on 08/02/2014.

Resource summary

Question Answer
Growth on Blood Agar plate Varies Depending on strain
Beta Haemolytic Strep. Characteristics Complete haemolysis- celar area around colony
Alpha Haemolytic Strep Partial Haemolysis- greenish tinge around colony
Gamma Strep No haemolysis
Lancefield Classification of Strep Based of cell wall polypeptides (identified using Ab's)
Lancefield Classifications A-H & K-U (The corresponding Ag's cause agglutination
Mild S. Pyogenes Ingections Impetigo
Serious S.Pyogenes Infections Cellulitis, Necratising Fasciitis
Eipdemiology- Source Usually exogenous (or unknown)
Eipdemiology- Mode of Transmission Contact/Resp. droplets
Eipdemiology- Host Immunity M-Protein Antigen confers some protection
Eipdemiology- Adhesion Factors Surface F. Proteins, Lipoteichoic Acid
Eipdemiology- Immune Evasion (M-Protein) Binds to host proteins, destabilising compliment and deactivating neutrophils
Eipdemiology- Immune Evasion (Variance) M-Protein structure is varied in to help evade the immune system
Eipdemiology- Immune Evasion (Capsule) Provides low immunogenicity
Eipdemiology- Immune Evasion (Streptokinase) Facilitates spread of bacteria
Eipdemiology- Exotoxins SPE A, B & C (A&C are superantigens) with all be pyogenic
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