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Flashcards

E.Coli

gina_evans0312 Medical Microbiology English 38 cards

Cards in this deck (38)

  1. 1DiarrheaChange in frequency/consistency of stools
  2. 2DysentryAbdominal pain, stool with blood/mucus
  3. 3E.Coli- Gram StainingGram -ve bacilli
  4. 4ColiformBacteria used to indicate sanitary conditions of food/water
  5. 5E.Coli- MovementHas peritrichous flagella
  6. 6E.Coli- Lactose FermenationPositive
  7. 7E.Coli- Culture MediaGrow on McConkey Agar
  8. 8E.Coli- Antigens (Somatic)Somatic O- Not species specific & causes many cross reactions
  9. 9E.Coli- Antigens (Flagellar)Flagellar H (Species specific, fewer cross reactions
  10. 10E.Coli- Strain RecognitionDone through strains H & O combination
  11. 11SerotypeA serologically distinguishable strain, leading to a specific disease syndrome
  12. 12E.Coli- Common InfectionsUrinary Tract Infections, Diarrhea
  13. 13PathotypeInfraspecific pathogen classification based on its pathogenicity in specific hosts
  14. 14E.Coli- ETECEnterotoxic E.Coli
  15. 15E.Coli- ETEC (CFAs)Colonisation Factor Antigens that allow bacteria to bind to intestinal epithelial cells
  16. 16E.Coli- ETEC (ST)Stable Toxin- released to stimulate cGMP production
  17. 17E.Coli- ETEC (LT)Labile Toxin- Released to increase cAMP production
  18. 18E.Coli- ETEC (Effect of ST & LT)Increase lumen electrolytes, leading to diarrhea
  19. 19E.Coli- ETEC (Infections)Travelers diarrhea, varies from mild to severe
  20. 20E.Coli- EPEC-Enteropathogenic E.Coli
  21. 21E.Coli- EPEC (Initial Attachment)Uses bundle forming pili
  22. 22E.Coli- EPEC (Intimate Attachment)Done through a Type 3 Secretory System
  23. 23E.Coli- EPEC (LEE)Locus Enteric Effacement- pathogenicity island containing a needle like structure that injects host cell wall with Tir protein
  24. 24E.Coli- EPEC (Tir Protein)Remains in host cell wall and allows E.Coli to bind using Intimin on bacterial cell wall
  25. 25E.Coli- EPEC (Effect on Cell)Binding creates lesions that destroy the microvilli
  26. 26E.Coli- EPEC (Infections)Diarrhea in children under 2
  27. 27E. Coli- EHEC/STEC/VTEC3 Names, 1 Strain of E.Coli
  28. 28E.Coli- EHECEnterohaemorrhagic E.Coli (due to bloody diarrhea)
  29. 29E.Coli- STECShiga Toxin Producing E. Coli- this strain produces Shiga toxin
  30. 30E.Coli- VTECVeryocytoxin Producing E.Coli
  31. 31E.Coli- EHEC/STEC/VTEC (Infections)Haemorrhagic colitis (blood in feces) and is linked to Serious Haemolytic Uremic Syndrome
  32. 32E.Coli- EHEC/STEC/VTEC (Reservoir)Cattle
  33. 33E.Coli- EHEC/STEC/VTEC (Sources)Contaminated meat/vegetables
  34. 34E.Coli- EHEC/STEC/VTEC (Binding)Binds through pathogenicity islands like EPEC strain
  35. 35E.Coli- EHEC/STEC/VTEC (Stx Phage)Encodes the Shiga toxin
  36. 36E.Coli- EHEC/STEC/VTEC (Shiga Secretion)Can't happen- no secretory system- so toxin is released by cell lysis (hence no antibiotics on infection)
  37. 37E.Coli- EHEC/STEC/VTEC (Receptor GB3)Target of Shiga toxin on Pantch cells (intestine) or kidney epithelial cells
  38. 38E.Coli- EHEC/STEC/VTEC (Effect of Shiga Toxin)Prevents protein synthesis- leading to RBC lysis and kidney damage

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Medical Microbiology (G.I Tract Infections) Flashcards on E.Coli, created by gina_evans0312 on 10/02/2014.
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gina_evans0312
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