Flashcards
E. Coli as a UTI
Cards in this deck (16)
- 1Host Defenses- UrineHigh osmolarity and urea concentration- antibacterial properties
- 2Host Defenses-SphinctersThey existed
- 3Part of UTI That Isn't SterileDistal urether
- 4Environment- E.ColiEndogenous intestinal bacteria
- 5E.Coli- Ascending Route of InfectionEndogenous intestine E.Coli colonise the female urethra and ascend into the bladder
- 6UPECUropathogenic E.Coli
- 7UPEC- AdhesinsBind to UTI epithelial cell receptors
- 8UPEC Adhesins- Type 1 FibriaeBind to to mannosideases (abundant in bladder cell epithelium)
- 9UPEC Adhesins- P. FimbriaeBind to glycolipids (abundant in renal epithelium)
- 10UPEC Adhesins- AdherenceAdherence activates TLRs, leading to cytokine production...
- 11TLR4 mutationsAssociated with ABU
- 12EPEC- Immune Response (Chemokine Receptor CXCR1)Associated with neutraphil movement across the epithelium
- 13CXCR1 DeficiencyAssociated with severe pyelenephritis
- 14EPEC Virulence Factors- SiderophoesIncrease possible metabolites i.e. Aerobactins to acquire iron
- 15EPEC Virulence Factors- ToxinsI.e. Haemolytics
- 16EPEC Virulence Factors- CapsulePrevents phagocytosis
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- Medical Microbiology (Urinary Tract Infections) Flashcards on E. Coli as a UTI, created by gina_evans0312 on 06/03/2014.
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- gina_evans0312
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